An Enigmatic Case of Skeletal Fluorosis: Inhalant-Induced Toxicity.

Autor: DeMarco KM; From the Naval Medical Center Portsmouth, Portsmouth, VA., Major JW, Young CR, Hassantoufighi A
Jazyk: angličtina
Zdroj: Clinical nuclear medicine [Clin Nucl Med] 2023 Oct 01; Vol. 48 (10), pp. e487-e488. Date of Electronic Publication: 2023 Aug 03.
DOI: 10.1097/RLU.0000000000004780
Abstrakt: Abstract: Skeletal fluorosis is more common in the developing world, but is occasionally seen in the United States. We present radiographic, scintigraphic, CT, and clinical images of a 26-year-old woman with rapidly progressive, debilitating, polyostotic periostitis, and diffuse osteosclerosis typical of skeletal fluorosis. Laboratory analyses supported this diagnosis. The source of excess fluoride intake was elusive until a concurrent mental health workup revealed the patient's proclivity for inhaling air-duster cans containing difluoroethane. Difluoroethane inhalant abuse is an increasingly reported cause of skeletal fluorosis that astute clinicians should recognize. Discontinuation and sobriety from this toxic agent are essential for recovery.
Competing Interests: Conflicts of interest and sources of funding: none declared.
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Databáze: MEDLINE