| Autor: |
Kia M; Department of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran., Nekooei F; Department of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran., Alipour AH; Department of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran., Hashemi SMA; Department of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran., Salimi V; Department of Virology, Tehran University of Medical Sciences, Tehran, Iran., Fattahi MJ; Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Lankarani KB; Health Policy Research Center, Institute of Heath, Shiraz University of Medical Sciences, Shiraz, Iran., Sarvari J; Department of Bacteriology and Virology, Shiraz University of Medical Sciences, Shiraz, Iran.; Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. |
| Abstrakt: |
Measles is an acute, highly contagious disease with a high mortality rate in children. Although vaccination has reduced measles incidence, outbreaks still occur. Therefore, in this study, we aimed to investigate the frequency of antimeasles immunoglobulin G (IgG) antibody (Ab) among students at Shiraz University of Medical Sciences (SUMS). Four hundred fifty SUMS students were enrolled in this cross-sectional study. Information on demographics and measles vaccination history was collected using a questionnaire. Participants were divided into two groups, including A and B, according to routine doses of measles vaccine and the national measles/rubella immunization program. The antimeasles IgG Abs were tested using a commercial Enzyme-Linked Immunosorbent Assay Kit. Participants ranged in age from 18 to 48 years, with a mean age of 22.2 (±4.3). Fifty percent of the subjects were male. Our results showed that 63.6% of the cases were positive for antimeasles IgG Abs. The seroprevalence of IgG Abs between groups A and B did not differ significantly ( p = 0.612). There was also no significant correlation between the seroprevalence of antimeasles IgG Abs and the age ( p = 0.43) or sex ( p = 0.24) of the subjects. The results showed that the frequency of antimeasles IgG Abs is lower than required to prevent the measles virus from circulating. Therefore, a booster vaccination may be necessary. |
