Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review.

Autor: Patel S; Vanderbilt University Medical Scholars Program Nashville Tennessee USA.; Meharry Medical College Nashville Tennessee USA., Kunnath AJ; School of Medicine Vanderbilt University Nashville Tennessee USA., Gallant JN; Department of Otolaryngology-Head & Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USA., Belcher RH; Department of Otolaryngology-Head & Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USA.
Jazyk: angličtina
Zdroj: OTO open [OTO Open] 2023 Aug 09; Vol. 7 (3), pp. e66. Date of Electronic Publication: 2023 Aug 09 (Print Publication: 2023).
DOI: 10.1002/oto2.66
Abstrakt: Objective: To perform a scoping review to characterize postoperative outcomes of pediatric patients (ages 0-18) with a history of congenital head and neck teratomas.
Data Sources: PubMed, EMBASE, Web of Science, Cochrane, Clinicaltrails.gov.
Review Methods: A search of multiple databases was performed. Studies were included if they detailed the surgical management and outcomes of pediatric patients with a history of congenital head and neck teratomas.
Results: One hundred and eight studies totaling 137 patients were identified. The median gestational age at birth was 37 weeks. Respiratory distress, prompting emergent endotracheal intubation or tracheostomy, was present in most patients (58%). The ex utero intrapartum treatment (EXIT) procedure was utilized for 21 (15%) patients. The teratomas were resected after a median duration of 4 days from birth. The most common postsurgical complications were vocal cord paralysis (3%), hemorrhage (2%), and tracheomalacia (2%). Death occurred perioperatively in 2 patients (2%). Twenty-six patients (19%) required additional surgery, and 5 patients (4%) needed adjuvant chemotherapy. Patients were monitored for a median duration of 24 months with a recurrence rate of 6%. Four recurrent cases (50%) had intracranial extension, and 88% of the recurrent cases were mature teratomas at initial histopathological diagnosis.
Conclusion: Most patients with congenital head and neck teratomas require emergent airway management perinatally. Excisional and surgical complications are rare, and most patients are cured of their disease with a single operation. Recurrent teratomas tend to have an intracranial extension and are likely to be of mature pathology at the time of initial diagnosis.
Competing Interests: No conflict to disclose for this study.
(© 2023 The Authors. OTO Open published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngology–Head and Neck Surgery Foundation.)
Databáze: MEDLINE
Externí odkaz: