Study of the Effects of Highly Diluted Sodium Sulfate and Interferon-Gamma.

Autor: Molodtsova IV; LLC 'MATERIA MEDICA HOLDING', Moscow, Russia., Khimich EO; LLC 'MATERIA MEDICA HOLDING', Moscow, Russia., Sosnenko ES; LLC 'MATERIA MEDICA HOLDING', Moscow, Russia., Petrova AO; LLC 'MATERIA MEDICA HOLDING', Moscow, Russia., Stepanov GO; LLC 'MATERIA MEDICA HOLDING', Moscow, Russia., Don ES; LLC 'MATERIA MEDICA HOLDING', Moscow, Russia. gavrilovaes@materiamedica.ru.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2023 Jul; Vol. 175 (3), pp. 327-330. Date of Electronic Publication: 2023 Aug 11.
DOI: 10.1007/s10517-023-05861-8
Abstrakt: High dilutions of solutions containing extremely small amounts of the initial substance can modify the biological effects of the initial substance molecules. Using terahertz spectroscopy, we studied the possibility of modifying the physicochemical properties of the initial substance by adding high dilutions of high-molecular-weight (IFNγ) and low-molecular-weight (Na2SO4) compounds. In addition, the modifying effect produced by high dilutions of a low-molecular electrolyte (a solution of Na 2 SO 4 salt) on the initial substance was confirmed by conductometry. This method allows measuring electrical conductivity that also depends on the physicochemical properties of the solution, namely, the number of ions and velocity of their movement. Statistically significant differences were shown between terahertz and conductometric characteristics of the initial solution (inorganic salt Na2SO4 or a protein IFNγ) and a solution, where high dilutions of the same substances were added in different concentrations. Interestingly, the differences were more pronounced for the biological molecule. Thus, it has been shown that high dilutions can change the properties of the initial solution; the effect is more pronounced for the protein solution.
(© 2023. Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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