Quantitative CT Analysis Based on Smoking Habits and Chronic Obstructive Pulmonary Disease in Patients with Normal Chest CT.
| Autor: | Byon JH, Jin GY, Han YM, Choi EJ, Chae KJ, Park EH |
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| Jazyk: | angličtina |
| Zdroj: | Journal of the Korean Society of Radiology [J Korean Soc Radiol] 2023 Jul; Vol. 84 (4), pp. 900-910. Date of Electronic Publication: 2023 Jul 14. |
| DOI: | 10.3348/jksr.2022.0130 |
| Abstrakt: | Purpose: To assess normal CT scans with quantitative CT (QCT) analysis based on smoking habits and chronic obstructive pulmonary disease (COPD). Materials and Methods: From January 2013 to December 2014, 90 male patients with normal chest CT and quantification analysis results were enrolled in our study [non-COPD never-smokers ( n = 38) and smokers ( n = 45), COPD smokers ( n = 7)]. In addition, an age-matched cohort study was performed for seven smokers with COPD. The square root of the wall area of a hypothetical bronchus of internal perimeter 10 mm (Pi10), skewness, kurtosis, mean lung attenuation (MLA), and percentage of low attenuation area (%LAA) were evaluated. Results: Among patients without COPD, the Pi10 of smokers (4.176 ± 0.282) was about 0.1 mm thicker than that of never-smokers (4.070 ± 0.191, p = 0.047), and skewness and kurtosis of smokers (2.628 ± 0.484 and 6.448 ± 3.427) were lower than never-smokers (2.884 ± 0.624, p = 0.038 and 8.594 ± 4.944, p = 0.02). The Pi10 of COPD smokers (4.429 ± 0.435, n = 7) was about 0.4 mm thicker than never-smokers without COPD (3.996 ± 0.115, n = 14, p = 0.005). There were no significant differences in MLA and %LAA between groups ( p > 0.05). Conclusion: Even on normal CT scans, QCT showed that the airway walls of smokers are thicker than never-smokers regardless of COPD and it preceded lung parenchymal changes. Competing Interests: Conflicts of Interest: The authors have no potential conflicts of interest to disclose. (Copyrights © 2023 The Korean Society of Radiology.) |
| Databáze: | MEDLINE |
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