Prognostic Nutritional Index as a Predictor of No-Reflow Occurrence in Patients With ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention.

Autor: Safak O; Department of Cardiology, Balıkesir University, Balıkesir, Turkey., Yildirim T; Department of Cardiology, Balıkesir University, Balıkesir, Turkey., Emren V; Department of Cardiology, İzmir Katip Çelebi University, İzmir, Turkey., Avci E; Department of Cardiology, Balıkesir University, Balıkesir, Turkey., Argan O; Department of Cardiology, Balıkesir University, Balıkesir, Turkey., Aktas Z; Department of Cardiology, Balıkesir State Hospital, Balıkesir, Turkey., Yildirim SE; Department of Cardiology, Balıkesir University, Balıkesir, Turkey., Akgun DE; Department of Cardiology, Kırklareli Training and Research Hospital, Kırklareli, Turkey., Kisacik HL; Department of Cardiology, Balıkesir University, Balıkesir, Turkey.
Jazyk: angličtina
Zdroj: Angiology [Angiology] 2024 Aug; Vol. 75 (7), pp. 689-695. Date of Electronic Publication: 2023 Aug 08.
DOI: 10.1177/00033197231193223
Abstrakt: Nutritional status and its index (Prognostic Nutritional Index, PNI) is an important prognostic factor for ST-segment elevation myocardial infarction (STEMI). The present study investigated whether PNI it is associated with no-reflow in patients with STEMI. In this retrospective study, 404 patients with STEMI and underwent primary percutaneous coronary intervention (pPCI) were consecutively included, between January 2016 and December 2018. No-reflow phenomenon (NRP) was detected in 103 (25.4%) patients. In multivariate logistic regression analysis C-reactive protein (CRP) (odds ratio (OR): 1.693, 95% confidence interval (CI): 1.126-2.547, P = .011), left ventricle ejection fraction (LVEF) (OR: 0.777, 95% CI: 0.678-0.891, P < .001), SYNTAX score (OR: 1.114, 95% CI: 1.050-1.183, P = .001), low density lipoprotein cholesterol (LDL-C) (OR: 1.033, 95% CI: 1.013-1.055, P = .002), hemoglobin level (OR: 0.572, 95% CI: 0.395-0.827, P = .003), PNI (OR: 0.554, 95% CI: 0.448-0.686, P < .001) were associated with NRP. The area under curve of PNI was significantly higher than albumin (z = 4.747, P < .001) and lymphocyte values (z = 3.481 P < .001). PNI was associated with no-reflow occurrence and mortality. So, PNI may be useful to predict NRP risk in patients with STEMI before pPCI.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE