Effects of exercise and cold-water exposure on microvascular muscle perfusion.

Autor: Huettel M; Center for Musculoskeletal Surgery Osnabrück (OZMC), Klinikum Osnabrück GmbH, Osnabrück, Germany., Schroeter S; Center for Musculoskeletal Surgery Osnabrück (OZMC), Klinikum Osnabrück GmbH, Osnabrück, Germany., Heiss R; Department of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Lutter C; Department of Orthopedics, University Medical Center Rostock, Rostock University Medical Center, Rostock, Germany., Golditz T; Department of Anesthesiology, Erlangen University Hospital Department of Anaesthesiology, Erlangen, Germany.; Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Hoppe MW; Movement and Training Science, Faculty of Sports Science, Leipzig University, Leipzig, Germany., Forst R; Department of Orthopaedics and Orthopaedic Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Hafez H; Center for Musculoskeletal Surgery Osnabrück (OZMC), Klinikum Osnabrück GmbH, Osnabrück, Germany., Engelhardt M; Center for Musculoskeletal Surgery Osnabrück (OZMC), Klinikum Osnabrück GmbH, Osnabrück, Germany., Grim C; Center for Musculoskeletal Surgery Osnabrück (OZMC), Klinikum Osnabrück GmbH, Osnabrück, Germany., Hotfiel T; Center for Musculoskeletal Surgery Osnabrück (OZMC), Klinikum Osnabrück GmbH, Osnabrück, Germany.; Department of Trauma and Orthopedic Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Jazyk: angličtina
Zdroj: Ultraschall in der Medizin (Stuttgart, Germany : 1980) [Ultraschall Med] 2023 Aug; Vol. 44 (4), pp. e191-e198. Date of Electronic Publication: 2023 Aug 08.
DOI: 10.1055/a-2080-2937
Abstrakt: Purpose: Microvascular blood flow (MBF) and its intramuscular regulation are of importance for physiological responsiveness and adaptation. The quantifiable in-vivo monitoring of MBF after cycling or systemic cold-water exposure may reveal new insights into capillary regulatory mechanisms. This study aimed to assess the role of exercise and cold therapy on MBF by using contrast-enhanced ultrasound (CEUS).
Methods: Twenty healthy athletes were recruited and randomly assigned to an intervention (IG) or a control group (CG). MBF was quantified in superficial (rectus femoris, RF) and deep muscle layers (vastus intermedius, VI). Representative perfusion parameters (peak enhancement (PE) and wash-in area under the curve (WiAUC)) were measured after a standardized measurement protocol for both groups at resting conditions (t 0 ) and after cycling (20 min., 70% Watt max, t 1 ) for both groups, after cold-water immersion exposure for IG (15 min., 12°C) or after precisely 15 minutes of rest for CG (t 2 ) and for both groups after 60 minutes of follow-up (t 3 ).
Results: At t 1 , MBF in VI increased significantly compared to resting conditions in both groups in VI (p= 0.02). After the cold-water exposure (t 2 ), there were no statistically significant changes in perfusion parameters as well as after 60 minutes of follow-up (t 3 ) (p = 0.14).
Conclusion: Cycling leads to an upregulation of MBF. However, cold exposure does not change the MBF. The implementation of CEUS during different physiological demands may provide deeper insight into intramuscular perfusion regulation and regenerative processes.
Competing Interests: The authors declare that they have no conflict of interest.
(Thieme. All rights reserved.)
Databáze: MEDLINE
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