Spatiotemporal Surveillance of SARS-CoV-2 in the Sewage of Three Major Urban Areas in Peru: Generating Valuable Data Where Clinical Testing Is Extremely Limited.

Autor:	Pardo-Figueroa B; Universidad de Ingenieria y Tecnologia (UTEC), Centro de Investigación y Tecnología del Agua (CITA), Jr. Medrano Silva 165, Lima 15063, Peru., Mindreau-Ganoza E; Universidad Nacional Mayor de San Marcos, Facultad de Ciencias Biológicas, Av. Germán Amézaga s/n, Lima 15081, Peru., Reyes-Calderon A; Universidad de Ingenieria y Tecnologia (UTEC), Centro de Investigación y Tecnología del Agua (CITA), Jr. Medrano Silva 165, Lima 15063, Peru., Yufra SP; Universidad Nacional de San Agustin de Arequipa, Departamento de Ingeniería Metalúrgica e Ingeniería Ambiental, Av. Independencia s/n, Arequipa 04001, Peru., Solorzano-Ortiz IM; Universidad de Ingenieria y Tecnologia (UTEC), Departamento de Ingeniería Ambiental, Jr. Medrano Silva 165, Lima 15063, Peru., Donayre-Torres AJ; Universidad de Ingenieria y Tecnologia (UTEC), Departamento de Bioingeniería, Jr. Medrano Silva 165, Lima 15063, Peru., Antonini C; Universidad de Ingenieria y Tecnologia (UTEC), Departamento de Ingeniería Industrial, Jr. Medrano Silva 165, Lima 15063, Peru., Renom JM; Universidad de Ingenieria y Tecnologia (UTEC), Departamento de Ciencias, Jr. Medrano Silva 165, Lima 15063, Peru., Quispe AM; Universidad de Ingenieria y Tecnologia (UTEC), Departamento de Bioingeniería, Jr. Medrano Silva 165, Lima 15063, Peru.; Universidad Continental, Escuela de Posgrado, Av. San Carlos 1980, Huancayo 12001, Peru., Mota CR; Universidade Federal de Minas Gerais, Departamento de Engenharia Sanitária e Ambiental, Escola de Engenharia, Av. Antonio Carlos, 6.627, 31270-901 Belo Horizonte, Brazil., Chernicharo CAL; Universidade Federal de Minas Gerais, Departamento de Engenharia Sanitária e Ambiental, Escola de Engenharia, Av. Antonio Carlos, 6.627, 31270-901 Belo Horizonte, Brazil., Carbajal MA; Ministerio de Vivienda Construcción y Saneamiento, Dirección de Saneamiento, Av. República de Panamá 3650, Lima 15073, Peru., Santa-María MC; Universidad de Ingenieria y Tecnologia (UTEC), Centro de Investigación y Tecnología del Agua (CITA), Jr. Medrano Silva 165, Lima 15063, Peru.; Universidad de Ingenieria y Tecnologia (UTEC), Departamento de Ingeniería Ambiental, Jr. Medrano Silva 165, Lima 15063, Peru.
Jazyk:	angličtina
Zdroj:	ACS ES&T water [ACS ES T Water] 2022 May 20; Vol. 2 (11), pp. 2144-2157. Date of Electronic Publication: 2022 May 20 (Print Publication: 2022).
DOI:	10.1021/acsestwater.2c00065
Abstrakt:	Peru has been severely affected by the COVID-19 pandemic. By January 2022, Peru had surpassed 200 000 COVID-19 deaths, constituting the highest death rate per capita worldwide. Peru has had several limitations during the pandemic: insufficient testing access, limited contact tracing, a strained medical infrastructure, and many economic hurdles. These limitations hindered the gathering of accurate information about infected individuals with spatial resolution in real time, a critical aspect of effectively controlling the pandemic. Wastewater monitoring for SARS-CoV-2 RNA offered a promising alternative for providing needed population-wide information to complement health care indicators. In this study, we demonstrate the feasibility and value of implementing a decentralized SARS-CoV-2 RNA wastewater monitoring system to assess the spatiotemporal distribution of COVID-19 in three major cities in Peru: Lima, Callao, and Arequipa. Our data on viral loads showed the same trends as health indicators such as incidence and mortality. Furthermore, we were able to identify hot spots of contagion within the surveyed urban areas to guide the efforts of health authorities. Viral decay in the sewage network of the cities studied was found to be negligible (<2%). Overall, our results support wastewater monitoring for SARS-CoV-2 as a valuable and cost-effective tool for monitoring the COVID-19 pandemic in the Peruvian context. Competing Interests: The authors declare no competing financial interest. (© 2022 The Authors. Published by American Chemical Society.)
Databáze:	MEDLINE
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