Segmentation-Based Analysis of T2- and T1-Weighted Dynamic Magnetic Resonance Images Provides Adequate Observer Agreement in the Evaluation of Interstitial Lung Disease.

Autor:	Ruano CA, Veiga J; From the Department of Radiology, Hospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central., Antunes N, Carvalho VB; From the Department of Radiology, Hospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central., Fernandes O, Borba A; Department of Pulmonology, Hospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central., Oliveira FPM; Department of Nuclear Medicine, Champalimaud Foundation., Moraes-Fontes MF; Department of Immuno-Oncology, Champalimaud Foundation., Bilhim T; Interventional Radiology Unit, Hospital Curry Cabral, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal., Irion KL; Department of Radiology, College of Medicine, University of Florida, Gainesville, FL.
Jazyk:	angličtina
Zdroj:	Journal of computer assisted tomography [J Comput Assist Tomogr] 2024 Jan-Feb 01; Vol. 48 (1), pp. 92-97. Date of Electronic Publication: 2023 Aug 07.
DOI:	10.1097/RCT.0000000000001524
Abstrakt:	Objective: The aim of the study is to quantify observer agreement in the magnetic resonance imaging (MRI) classification of inflammatory or fibrotic interstitial lung disease (ILD). Methods: Our study is a preliminary analysis of a larger prospective cohort. The MRI images of 18 patients with ILD (13 females; mean age, 65 years) were acquired in a 1.5 T scanner and included axial fat-saturated T2-weighted (T2-WI, n = 18) and coronal fat-saturated T1-weighted images before and 1, 3, 5, and 10 minutes after gadolinium administration (n = 16). The MRI studies were evaluated with 2 different methods: a qualitative evaluation (visual assessment and measurement of few regions of interest; evaluations were performed independently by 5 radiologists and 3 times by 1 radiologist) and a segmentation-based analysis with software extraction of signal intensity values (evaluations were performed independently by 2 radiologists and twice by 1 radiologist). Interstitial lung disease was classified as inflammatory or fibrotic, based on previously described imaging criteria. Results: Regarding the qualitative evaluation, intraobserver agreement was excellent (κ = 0.92, P < 0.05) for T2-WI and fair (κ = 0.29, P < 0.05) for T1 dynamic study, while interobserver agreement was moderate (κ = 0.56, P < 0.05) and poor (κ = 0.11, P = 0.18), respectively. In contrast, upon segmentation-based analysis, intraobserver and interobserver agreement were excellent for T2-WI (κ = 0.886, P < 0.001; κ = 1.00, P < 0.001; respectively); for T1-WI, intraobserver agreement was excellent (κ = 0.87, P < 0.05) and interobserver agreement was good (κ = 0.75, P < 0.05). Conclusions: Segmentation-based MRI analysis is more reproducible than a qualitative evaluation with visual assessment and measurement of few regions of interest. Competing Interests: The authors declare no conflict of interest. (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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