Clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.

Autor:	Ndulue CN; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Jisieike-Onuigbo NN; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Okwesa NJ; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Anyanor A; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Ozuemba BC; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Osakwe N; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Oguejiofor F; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Eze H; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Kalu AO; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria., Odenigbo CU; Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Jazyk:	angličtina
Zdroj:	African health sciences [Afr Health Sci] 2023 Mar; Vol. 23 (1), pp. 592-595.
DOI:	10.4314/ahs.v23i1.62
Abstrakt:	Thrombotic thrombocytopenic purpura (TTP) is a rare variant of thrombotic microangiopathy. We report a case of TTP in a Nigerian chronic kidney disease (CKD) patient who was previously on clopidogrel. The features of TTP resolved soon after clopidogrel was withdrawn. Clopidogrel is a cardio-protective anti-platelet drug used in CKD patients at risk of dyspepsia. However, its potential to cause TTP should be recognized and considered in acute kidney injury (AKI) patients previously on clopidogrel. (© 2023 Ndulue CN et al.)
Databáze:	MEDLINE
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