Magnetic solid phase extraction of aminoglycosides residue in chicken egg samples using Fe 3 O 4 -GO-Agarose-Chitosan composite.

Autor: Sajjad M; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan., Almufarij R; Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia., Ali Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan., Sajid M; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan. Electronic address: dr.msajid@bzu.edu.pk., Raza N; Department of Chemistry, College of Science, Imam Muhammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia; Department of Chemistry, Govt. Alamdar Hussain Islamia Degree College, Multan, Pakistan. Electronic address: nadeemr890@gmail.com., Manzoor S; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan., Hayat M; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan., Abdelrahman EA; Department of Chemistry, College of Science, Imam Muhammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia; Chemistry Department, Faculty of Science, Benha University, Benha 13518, Egypt.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Jan 01; Vol. 430, pp. 137092. Date of Electronic Publication: 2023 Aug 02.
DOI: 10.1016/j.foodchem.2023.137092
Abstrakt: Difficulties in identification of drug residues in food products arise due to their trace amounts in complex matrices. An eco-friendly and low-cost agarose-chitosan-magnetic graphene oxide based adsorbent was synthesized and employed for determination of aminoglycosides from chicken egg samples through HPLC. Synthesized adsorbent was characterized by SEM, FTIR, XRD, and VSM. Among two investigated aminoglycosides, streptomycin was derivatized with ninhydrin while gentamicin was detected without its derivatization. Impact of experimental variables such as adsorbent dose, extraction time, temperature, pH, and analyte concentration on extraction efficiency was investigated. Statistical analysis for determination of streptomycin and gentamicin demonstrated excellent linearity in the range of 0.2-1.6 µg kg -1 , LOQ of 0.3 and 0.6 µg kg -1 for streptomycin and gentamicin, respectively and LOD of 0.1 and 0.19 µg kg -1 for streptomycin and gentamicin, respectively with RSD of 2.5% and recoveries up to 94%. Regeneration studies revealed that composite film can be used four times without considerable reduction in its extraction efficiency.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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