Beneficial Short-Term Effects of Bariatric Surgery on Nutritional Inflammatory Profile and Metabolic Biomarkers.

Autor: Seva DC; Post Graduate Program of Interdisciplinary Health Sciences, Universidade Federal de São Paulo, Campus Baixada Santista, Rua Silva Jardim, 136 - Térreo, Vila Matias, Santos, 11015020, Brazil., Mônico-Neto M; Post Graduate Program of Interdisciplinary Health Sciences, Universidade Federal de São Paulo, Campus Baixada Santista, Rua Silva Jardim, 136 - Térreo, Vila Matias, Santos, 11015020, Brazil. marcosmoniconeto@gmail.com.; Post Graduate Program in Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil. marcosmoniconeto@gmail.com.; BariMais - Medicina Integrada, São Paulo, Brazil. marcosmoniconeto@gmail.com., Antunes HKM; Post Graduate Program of Interdisciplinary Health Sciences, Universidade Federal de São Paulo, Campus Baixada Santista, Rua Silva Jardim, 136 - Térreo, Vila Matias, Santos, 11015020, Brazil.; Post Graduate Program in Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Biosciences, Universidade Federal de São Paulo, Santos, Brazil., Pino JMV; Department of Bioquimic, Universidade Federal de São Paulo, São Paulo, Brazil., Bittencourt LRA; Post Graduate Program in Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil., Galvão TD; BariMais - Medicina Integrada, São Paulo, Brazil., Dâmaso AR; Post Graduate Program of Nutrition, Paulista Medicine School, Universidade Federal de São Paulo (UNIFESP-EPMP), São Paulo, Brazil., Oyama LM; Post Graduate Program of Nutrition, Paulista Medicine School, Universidade Federal de São Paulo (UNIFESP-EPMP), São Paulo, Brazil.; Department of Physiology Paulista Medicine School, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Shivappa N; Cancer Prevention and Control Program, University of South Carolina, Columbia, SC, USA.; Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.; Department of Nutrition, Connecting Health Innovations LLC (CHI), Columbia, SC, USA., Hébert JR; Cancer Prevention and Control Program, University of South Carolina, Columbia, SC, USA.; Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.; Department of Nutrition, Connecting Health Innovations LLC (CHI), Columbia, SC, USA., Tufik S; Post Graduate Program in Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil., da Silveira Campos RM; Post Graduate Program of Interdisciplinary Health Sciences, Universidade Federal de São Paulo, Campus Baixada Santista, Rua Silva Jardim, 136 - Térreo, Vila Matias, Santos, 11015020, Brazil.
Jazyk: angličtina
Zdroj: Obesity surgery [Obes Surg] 2023 Sep; Vol. 33 (9), pp. 2789-2798. Date of Electronic Publication: 2023 Aug 04.
DOI: 10.1007/s11695-023-06743-8
Abstrakt: Purpose: Bariatric surgery (BS) has several potential metabolic benefits. However, little is known about its impact on changes in the inflammatory potential of diet and its effect on inflammatory and metabolic markers. This study aimed to assess the short-term beneficial effects of BS on dietary inflammatory potential and inflammatory and metabolic markers.
Materials and Methods: Participants (n = 20) were evaluated 3 months before and after BS. Body mass, body mass index, anthropometric measurements, fat mass, fat-free mass, visceral fat, skeletal muscle mass, basal metabolic rate, serum lipids, HOMA-IR, QUICKI and inflammatory markers, including leptin, adiponectin, adiponectin/leptin ratio and plasminogen activator inhibitor-1 (PAI-1), were evaluated. Diet data were collected using a 3-day diet record and the dietary inflammatory index (DII®) and energy-adjusted dietary inflammatory index (E-DII TM ) scores were computed.
Results: There was a reduction in DII® (2.56 vs 2.13) and E-DII TM (2.18 vs 0.45) indicating an improvement in inflammatory nutritional profile. Moreover, there were increases in the adiponectin/leptin ratio (0.08 vs 0.21) and QUICKI scores (0.31 vs 0.37), and reductions in leptin (36.66 vs 11.41 ng/ml) and HOMA-IR scores (3.93 vs 1.50). There were also improvements in body composition and anthropometric parameters.
Conclusions: BS promotes changes in metabolic profile, inflammatory state and food intake and these modifications appeared to be associated with improvements in diet-related inflammation, an increase in the adiponectin/leptin ratio and a reduction in leptin. These results contribute to knowledge on the contribution bariatric surgery can make to the treatment of obesity and the reduction of related comorbidities.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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