Estimation of Gingival Crevicular Blood as Noninvasive Method to Determine the Blood Glucose Level: A Comparative Study.

Autor:	Dash KC; Department of Oral and Maxillofacial Pathology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India., Ramanna PK; Department of Prosthodontics, Crown and Bridge and Implantology, Vydehi Institute of Dental Sciences and Research Hospital, Bengaluru, Karnataka, India., Varghese LJ; Department of Oral and Maxillofacial Surgery, Sree Anjaneya Institute of Dental Sciences, Calicut, Kerala, India, Phone: +91 9847638752, e-mail: linjacobvarghese@gmail.com., Reddy U; Department of Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), NITTE (Deemed to be University), Mangaluru, Karnataka, India., Nambiar S; Department of Periodontology, KMCT Dental College, Calicut, Kerala, India., Patel A; Department of Oral and Maxillofacial Pathology and Oral Microbiology, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Gujarat, India., Mishra D; Department of Periodontology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.
Jazyk:	angličtina
Zdroj:	The journal of contemporary dental practice [J Contemp Dent Pract] 2023 Jun 01; Vol. 24 (6), pp. 381-384. Date of Electronic Publication: 2023 Jun 01.
DOI:	10.5005/jp-journals-10024-3473
Abstrakt:	Aim: The current study's aim was to assess gingival crevicular blood as a noninvasive method to measure blood glucose levels. Materials and Methods: The current study comprised a total of 50 patients who had been diagnosed with chronic periodontitis and age was ≥30 years old. The study's procedures were carried out after receiving informed consent. For finger capillary blood collection method, a sterile lancet was used to prick the finger and a drop of blood was taken, for gingival crevicular blood collection method, blood was taken from the gingival margin of the chosen site, and for venous blood collection method with the aid of a disposable syringe, a venous blood sample was taken from the patient's antecubital fossa for determining blood glucose levels. One-way analysis of variance (ANOVA) was used to examine the differences between the three methodologies' significance, and Karl Pearson's correlation ( r ) was used to determine their correlation. Results: The maximum glucose level was found in venous blood (187.78 ± 18.23), followed by finger capillary blood (181.88 ± 21.67) and gingival crevicular blood (169.04 ± 11.24). And there was no significant difference between the different blood collection methods ( p > 0.05). The positive significant correlation was found between gingival crevicular blood and finger capillary blood ( r = 0.912, p < 0.001). Correlation with gingival crevicular blood and venous blood showed a positive correlation ( r = 0.898, p < 0.001). Correlation between venous blood and finger capillary blood also showed a strong positive correlation ( r = 0.988, p < 0.001). Conclusion: In conclusion, the findings of the current study suggest that blood drawn from the gingival crevicular during a clinical examination may be a great source for glucometric analysis. The gingival crevicular blood may show to be a promising technique for routine dental office screening for diabetes mellitus in periodontal patients, even if capillary/venous blood samples used for diabetes mellitus screening are the gold standard. Clinical Significance: Oral health is crucial for the early detection of many systemic disorders. As a result, dentists are crucial in the screening for systemic disorders. One of the prevalent chronic disorders is diabetes. Any systemic disease that is detected early enough can avoid long-term problems.
Databáze:	MEDLINE
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