Late complications after allogeneic hematopoietic cell transplant: What primary care physicians can do.

Autor: Granat LM; Chief Resident, Department of Internal Medicine, Cleveland Clinic, Cleveland, OH granatl2@ccf.org., Ondeck M; PGY3, Department of Internal Medicine, Cleveland Clinic, Cleveland, OH., Osantowski B; PGY3, Department of Internal Medicine, Cleveland Clinic, Cleveland, OH., Sheu M; PGY3, Department of Internal Medicine, Cleveland Clinic, Cleveland, OH., Ganesan V; PGY3, Department of Internal Medicine, Cleveland Clinic, Cleveland, OH., Rotz S; Staff Physician, Department of Pediatric Hematology, Oncology, and Blood and Marrow Transplant, Cleveland Clinic, Cleveland, OH; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH., Hamilton BK; Staff Physician, Blood and Marrow Transplant Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH; Associate Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
Jazyk: angličtina
Zdroj: Cleveland Clinic journal of medicine [Cleve Clin J Med] 2023 Aug 01; Vol. 90 (8), pp. 499-508. Date of Electronic Publication: 2023 Aug 01.
DOI: 10.3949/ccjm.90a.23006
Abstrakt: Survivors of allogeneic hematopoietic cell transplant (HCT) face the risk of many serious complications in the long term, which primary care physicians play an integral role in recognizing and treating. In this review, the authors summarize the most common complications that primary care physicians see after HCT recipients return to their care: chronic graft-vs-host disease; cardiovascular, metabolic, endocrine, rheumatologic, orthopedic, infectious, neurologic, and cognitive complications; secondary malignancies; psychiatric disorders; and impairments in quality of life and sexual health. Also discussed are health maintenance and screening recommendations for this patient population.
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Databáze: MEDLINE