Intravascular Tumor Extension and Pulmonary Tumor Embolism in Children With Solid Malignancies: Is There a Role for Inferior Vena Cava Filters?

Autor: Trinder SM; Department of Hematology, Oncology, and Bone Marrow Transplant Perth Children's Hospital, Nedlands., Ruhayel SD; Department of Hematology, Oncology, and Bone Marrow Transplant Perth Children's Hospital, Nedlands., Gottardo NG; Department of Hematology, Oncology, and Bone Marrow Transplant Perth Children's Hospital, Nedlands., McLaren CA; Department of Medical Imaging, Perth Children's Hospital, Nedlands.; Curtin Medical School, Curtin University, Bentley., Ryan AL; Department of Hematology, Oncology, and Bone Marrow Transplant Perth Children's Hospital, Nedlands.; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA., Roebuck DJ; Department of Medical Imaging, Perth Children's Hospital, Nedlands.; Division of Pediatrics, Medical School, University of Western Australia, Crawley, Australia.
Jazyk: angličtina
Zdroj: Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2023 Nov 01; Vol. 45 (8), pp. 467-471. Date of Electronic Publication: 2023 Jul 27.
DOI: 10.1097/MPH.0000000000002731
Abstrakt: Intravascular tumor extension is an uncommon complication of solid malignancies that, when present in the inferior vena cava (IVC), can result in fatal pulmonary tumor embolism. Currently, neoadjuvant chemotherapy and surgery are the mainstays of treatment; however, there are no consensus guidelines for management. We describe three cases of pediatric solid malignancies with associated IVC extension and pulmonary tumor embolism. We hypothesize that there is scope for IVC filter placement in such cases to mitigate the risk of fatal pulmonary tumor embolism.
Competing Interests: S.D.R. is partly funded by the Simon Lee Foundation. The remaining authors declare no conflict of interest.
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Databáze: MEDLINE