Health of wild fish exposed to contaminants of emerging concern in freshwater ecosystems utilized by a Minnesota Tribal community.

Autor: Deere JR; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA., Jankowski MD; United States Environmental Protection Agency, Seattle, Washington, USA., Primus A; Hubbs Seaworld Research Institute, San Diego, California, USA., Phelps NBD; Department of Fisheries, Wildlife and Conservation Biology, College of Food, Agricultural and Natural Resource Sciences, University of Minnesota, St. Paul, Minnesota, USA., Ferrey M; Minnesota Pollution Control Agency, St. Paul, Minnesota, USA., Borucinska J; Department of Biology, University of Hartford, West Hartford, Connecticut, USA., Chenaux-Ibrahim Y; Grand Portage Band of Lake Superior Chippewa, Biology and Environment, Grand Portage, Minnesota, USA., Isaac EJ; Grand Portage Band of Lake Superior Chippewa, Biology and Environment, Grand Portage, Minnesota, USA., Singer RS; Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA., Travis DA; The Marine Mammal Center, Sausalito, California, USA., Moore S; Grand Portage Band of Lake Superior Chippewa, Biology and Environment, Grand Portage, Minnesota, USA., Wolf TM; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.
Jazyk: angličtina
Zdroj: Integrated environmental assessment and management [Integr Environ Assess Manag] 2024 May; Vol. 20 (3), pp. 846-863. Date of Electronic Publication: 2023 Aug 17.
DOI: 10.1002/ieam.4822
Abstrakt: Fish serve as indicators of exposure to contaminants of emerging concern (CECs)-chemicals such as pharmaceuticals, hormones, and personal care products-which are often designed to impact vertebrates. To investigate fish health and CECs in situ, we evaluated the health of wild fish exposed to CECs in waterbodies across northeastern Minnesota with varying anthropogenic pressures and CEC exposures: waterbodies with no human development along their shorelines, those with development, and those directly receiving treated wastewater effluent. Then, we compared three approaches to evaluate the health of fish exposed to CECs in their natural environment: a refined fish health assessment index, a histopathological index, and high-throughput (ToxCast) in vitro assays. Lastly, we mapped adverse outcome pathways (AOPs) associated with identified ToxCast assays to determine potential impacts across levels of biological organization within the aquatic system. These approaches were applied to subsistence fish collected from the Grand Portage Indian Reservation and 1854 Ceded Territory in 2017 and 2019. Overall, 24 CECs were detected in fish tissues, with all but one of the sites having at least one detection. The combined implementation of these tools revealed that subsistence fish exposed to CECs had histological and macroscopic tissue and organ abnormalities, although a direct causal link could not be established. The health of fish in undeveloped sites was as poor, or sometimes poorer, than fish in developed and wastewater effluent-impacted sites based on gross and histologic tissue lesions. Adverse outcome pathways revealed potential hazardous pathways of individual CECs to fish. A better understanding of how the health of wild fish harvested for consumption is affected by CECs may help prioritize risk management research efforts and can ultimately be used to guide fishery management and public health decisions. Integr Environ Assess Manag 2024;20:846-863. © 2023 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
(© 2023 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).)
Databáze: MEDLINE
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