Overt Hypothyroidism Status Post Pfizer-BioNTech Vaccination: A Case Study.

Autor: Nandennagari S; Medicine, Avalon University School of Medicine, Willemstad, CUW., Annam P; Surgery, Avalon University School of Medicine, Willemstad, CUW., Naidu N; Family Medicine, American University of Barbados, Wildey, BRB., Vegesna P; Family Medicine, American University of Barbados, Wildey, BRB., Bethala K; Pharmacology and Therapeutics, Centre of Excellence in Pharmaceutical Sciences, School of Pharmacy, KPJ Healthcare University College, Nilai, MYS.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Jun 30; Vol. 15 (6), pp. e41180. Date of Electronic Publication: 2023 Jun 30 (Print Publication: 2023).
DOI: 10.7759/cureus.41180
Abstrakt: Coronavirus disease (COVID-19) is among the most contagious viral illnesses, affecting millions worldwide. Although precautions such as social distancing, hand sanitizing, and the use of masks decreased the transmission of the virus, the situation went uncontrolled until vaccination came to light. Vaccination was vital in limiting the incidence, prevalence, and severity caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on the mechanism, several types of vaccines, such as Pfizer-BioNTech, Moderna, AstraZeneca, Johnson & Johnson, and Covaxin, were approved by the US Food and Drug Administration (FDA). A booster dose was implemented as the vaccine's effectiveness decreased with time. Several side effects, such as fever, soreness around the injection site, fatigue, chills, muscle weakness, and headache, have been reported after vaccination with Pfizer-BioNTech, but thyroid dysfunction is relatively rare. Several case reports and even case series describing links between COVID-19 vaccination and various types of thyroid dysfunction have appeared in the literature. However, the exact reasons have yet to be explained. This report presents the case of a healthy 50-year-old woman diagnosed with overt hypothyroidism three weeks after the administration of the Pfizer-BioNTech vaccine.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Nandennagari et al.)
Databáze: MEDLINE