The total artificial heart: where have we been, where are we now, where are we going?

Autor: Arabía FA; Advanced Heart Program, Banner - University Medical Group Phoenix, Phoenix, USA.; Surgery and Medicine, University of Arizona College of Medicine, Phoenix, , Phoenix, AZ USA., Murray CF; DCC, University of Arizona, Phoenix, AZ USA.
Jazyk: angličtina
Zdroj: Indian journal of thoracic and cardiovascular surgery [Indian J Thorac Cardiovasc Surg] 2023 Jul; Vol. 39 (Suppl 1), pp. 198-205. Date of Electronic Publication: 2023 Jul 25.
DOI: 10.1007/s12055-023-01559-8
Abstrakt: The incidence and prevalence of end-stage heart failure continue to rise; however, the number of donor hearts available for transplantation continues to be limited. Therefore, alternatives to transplantation, such as the use of total artificial hearts (TAH), are necessary. The long and winding road to the development and implantation of the ideal TAH remains under construction. Although efforts have been ongoing for almost a century, researchers and clinicians continue to improve currently available TAHs and design and construct new models. With mortality and morbidity rates decreasing, particularly at high-volume centers with a dedicated team and carefully selected patients, the use of TAHs as a bridge to transplantation, and even destination therapy in clinical trials, the future of TAHs is bright.
Competing Interests: Conflict of interestDr. Francisco Arabia serves as a consultant to Syncardia Systems, LLC, Carmat TAH, and BiVACOR TAH. Catherine Friederich Murray, MNLM has nothing to disclose.
(© Indian Association of Cardiovascular-Thoracic Surgeons 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
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