Giant squamous cell carcinoma developed on a mesh-related enterocutaneous fistula: A case report.

Autor:	Fajardo R; School of Medicine, Universidad de los Andes, Bogotá, Colombia; Department of Surgery, Fundación Santa Fe de Bogotá, Colombia., Núñez-Rocha RE; School of Medicine, Universidad de los Andes, Bogotá, Colombia; Department of Surgery, Fundación Santa Fe de Bogotá, Colombia. Electronic address: re.nunez@uniandes.edu.co., Gómez-Carrillo D; School of Medicine, Universidad de los Andes, Bogotá, Colombia; Department of Surgery, Fundación Santa Fe de Bogotá, Colombia., Pedraza JD; School of Medicine, Universidad de los Andes, Bogotá, Colombia., López R; School of Medicine, Universidad de los Andes, Bogotá, Colombia; Department of Pathology and Laboratory Medicine, Fundación Santa Fe de Bogotá, Colombia., Girón F; School of Medicine, Universidad de los Andes, Bogotá, Colombia; Department of Surgery, Fundación Santa Fe de Bogotá, Colombia.
Jazyk:	angličtina
Zdroj:	International journal of surgery case reports [Int J Surg Case Rep] 2023 Aug; Vol. 109, pp. 108581. Date of Electronic Publication: 2023 Jul 27.
DOI:	10.1016/j.ijscr.2023.108581
Abstrakt:	Introduction: Squamous cell carcinoma degeneration on enterocutaneous fistulas (EF) is infrequent. There are some reports of malignant conversion in Crohn's disease-associated fistulas. Literature about the malignant development of mesh-related EF is even more limited. Presentation of the Case: A 66-year-old patient who developed necrotizing pancreatitis was managed through an open necrosectomy approach with a prolonged open abdomen that derived an incisional hernia which was repaired using a synthetic mesh. Years later, the patient was admitted to the service because of hypovolemic shock due to gastrointestinal bleeding. An abdominal wound with mesh exposition and cloudy discharge was observed. A high-output enterocutaneous fistula diagnosis was established. After an institutional surgical committee, a surgical approach was defined, a 60 cm en-block resection of the involved small bowel was done, and the surgical specimen was obtained for histopathological analysis. Discussion: The use of prosthetic mesh in the case of incisional hernias is associated with a higher incidence of complications. However, there is no evidence of the development of squamous cell carcinoma developed on a mesh-related enterocutaneous fistula. This is a condition associated with Chron's disease and its diagnosis should be suspected by the exacerbation of local signs and symptoms. The scarce literature published suggests that this pathology can be managed by radical surgery and even chemoradiation, the last one required only for patients with associated Chron's disease. Conclusion: Squamous Cell Carcinoma developed on a mesh-related enterocutaneous fistula is a rare condition with no classic signs and symptoms that allow diagnostic identification. Competing Interests: Declaration of competing interest Nothing to disclose. (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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