Antiviral and Antibacterial Cold Spray Coating Application on Rubber Substrate, Disruption in Disease Transmission Chain.

Autor: Saha DC; Fatigue and Stress Analysis Laboratory, Department of Mechanical & Mechatronics Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1 Canada., Boegel SJ; Department of Chemical Engineering, University of Waterloo, Waterloo, ON N2L 3G1 Canada., Tanvir S; Department of Chemical Engineering, University of Waterloo, Waterloo, ON N2L 3G1 Canada., Nogueira CL; Department of Chemical Engineering, University of Waterloo, Waterloo, ON N2L 3G1 Canada., Aucoin MG; Department of Chemical Engineering, University of Waterloo, Waterloo, ON N2L 3G1 Canada., Anderson WA; Department of Chemical Engineering, University of Waterloo, Waterloo, ON N2L 3G1 Canada., Jahed H; Fatigue and Stress Analysis Laboratory, Department of Mechanical & Mechatronics Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1 Canada.
Jazyk: angličtina
Zdroj: Journal of thermal spray technology [J Therm Spray Technol] 2023; Vol. 32 (4), pp. 818-830. Date of Electronic Publication: 2023 Feb 09.
DOI: 10.1007/s11666-023-01553-x
Abstrakt: The objective of this study was to prepare a copper-coated rubber surface using cold spray technology with improved virucidal and antimicrobial properties to fight against highly transmissible viruses and bacteria. A successful cold spray coating was produced using irregular-shaped pure Cu powder on an escalator handrail rubber. The powder particles and the deposited coatings (single and double pass) were characterized in terms of particle morphology and size distribution, coating surface and coat/substrate cross-section properties. The bonding between powder and rubber surfaces was purely mechanical interlocking. The Cu powder penetration depth within the rubber surface increases with a number of depositions pass. The virucidal properties of the coated surface were tested utilizing surrogates for SARS-CoV-2: HCoV-229E, a seasonal human coronavirus, and baculovirus, a high-titer enveloped insect cell virus. A double-pass coated surface showed significant baculovirus inactivation relative to a bare rubber control surface after 2-h (approximately 1.7-log) and 4-h (approximately 6.2-log), while a 4-h exposure reduced HCoV-229E titer to below the limit of detection. A similar microbial test was performed using E. coli, showing a 4-log microbial reduction after 2-h exposure relative to the bare rubber. These promising results open a new application for cold spray in the health sector.
Supplementary Information: The online version contains supplementary material available at 10.1007/s11666-023-01553-x.
(© ASM International 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
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