Guillain-Barré syndrome associated with SARS-CoV-2 infection: A case series from 4 Colombian cities during the pandemic.

Autor:	Cerón Blanco N; Universidad del Rosario, Bogotá, Colombia.; Residente de Neurología, Fundación Cardioinfantil Instituto de Cardiologia, Bogotá, Colombia., Rodríguez Quintana JH; Universidad del Rosario, Bogotá, Colombia.; Neurólogo, Fundación Cardioinfantil Instituto de Cardiología, Bogotá, Colombia.; Neurólogo, Universidad del Rosario, Bogotá, Colombia.; Hospital Universitario Mayor y el Grupo NeuRos (Grupo de investigación en neurociencias de la Universidad del Rosario), Colombia., Valencia Mendoza MC; Universidad del Rosario, Bogotá, Colombia.; Residente de Neurología, Fundación Cardioinfantil Instituto de Cardiologia, Bogotá, Colombia., Forero Botero CA; Neurólogo, Fundación Santa Fe de Bogotá, Bogotá, Colombia., Rodríguez LC; Fisiatra, Fundación Santa Fe de Bogotá, Bogotá, Colombia., Carrillo Villa S; Neuróloga, Fundación Cardiovascular de Colombia, Santander, Colombia.; Clínica San Luis de Bucaramanga, Colombia., Gómez Mazuera AM; Neuróloga, Fundacion Santa Fe de Bogotá, Bogotá, Colombia., Angarita Díaz JA; Neurólogo, Universidad Nacional de Colombia - Sede Bogotá, Bogotá, Colombia.; Universidad Surcolombiana, Neiva, Colombia.; Clínica Mediláser de Neiva (Departamento del Huila), Colombia., Uribe García B; Universidad de Manizales, Manizales, Colombia.; Clínica Ospedale en Manizales, Colombia., Bermúdez Riveros CC; Universidad del Rosario, Bogotá, Colombia.; Neurólogo, Universidad del Rosario, Bogotá, Colombia., Alban J; Universidad Surcolombiana, Neiva, Colombia.
Jazyk:	angličtina
Zdroj:	Neurology perspectives [Neurol Perspect] 2022 Oct-Dec; Vol. 2 (4), pp. 232-239. Date of Electronic Publication: 2022 Jun 30.
DOI:	10.1016/j.neurop.2022.06.004
Abstrakt:	SARS-CoV-2 infection has been associated with multiple neurological manifestations. One such manifestation, which has been described since the early stages of the COVID-19 pandemic and is relevant for current neurological practice, is Guillain-Barré syndrome (GBS). The literature describes neurotoxic mechanisms of the virus itself and the possible pathways by which it may affect the peripheral nerves in experimental studies; however, we still lack information on the mechanisms causing the immune response that gives rise to GBS in the context of SARS-CoV-2 infection. Colombia is one of the Latin American countries worst affected by the pandemic, with the third-highest number of cases in the region; thus, it is essential to recognise GBS, as this potential postinfectious complication may severely compromise the patient's functional status in the absence of timely diagnosis and treatment. We present a series of 12 cases of GBS associated with SARS-CoV-2 infection from hospitals in 4 different Colombian cities and describe the clinical presentation, laboratory and electrophysiological study findings, and treatment. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2022 Sociedad Española de Neurología. Published by Elsevier España, S.L.U.)
Databáze:	MEDLINE
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