Intestinal Immune Cell Populations, Barrier Function, and Microbiomes in Broilers Fed a Diet Supplemented with Chlorella vulgaris .

Autor: Lee JY; Department of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea., Yoon JH; Department of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea., An SH; Department of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea., Cho IH; Department of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea., Lee CW; Department of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea., Jeon YJ; Department of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea., Joo SS; Department of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea., Ban BC; Department of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea., Lee JY; Animal Genetic Resources Research Center, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Republic of Korea., Jung HJ; Animal Nutrition and Physiology Team, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Republic of Korea., Kim M; Animal Nutrition and Physiology Team, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Republic of Korea., Kim ZH; Microbial Research Department, Nakdonggang National Institute of Biological Resources (NNIBR), Sangju 37242, Republic of Korea., Jung JY; Microbial Research Department, Nakdonggang National Institute of Biological Resources (NNIBR), Sangju 37242, Republic of Korea., Kim M; Department of Animal Science, College of Natural Resources & Life Science, Pusan National University, Miryang 50463, Republic of Korea.; Life and Industry Convergence Research Institute, Pusan National University, Miryang 50463, Republic of Korea., Kong C; Department of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea.; Department of Animal Science, Kyungpook National University, Sangju 37224, Republic of Korea.; Research Institute of Horse Industry, Kyungpook National University, Sangju 37224, Republic of Korea.
Jazyk: angličtina
Zdroj: Animals : an open access journal from MDPI [Animals (Basel)] 2023 Jul 21; Vol. 13 (14). Date of Electronic Publication: 2023 Jul 21.
DOI: 10.3390/ani13142380
Abstrakt: This study aimed to evaluate the effects of dietary Chlorella vulgaris (CV) on the distribution of immune cells, intestinal morphology, intestinal barrier function, antioxidant markers, and the cecal microbiome in 10-day-old broiler chickens. A total of 120 day-old Ross 308 male broiler chicks were assigned to two dietary treatments using a randomized complete block design, with body weight as the blocking factor. Birds fed a diet containing CV showed an increase in CD4 + T cells ( p < 0.05) compared to those fed the control diet. The relative mRNA expression of intestinal epithelial barrier function-related markers (occludin and avian β-defensin 5) was elevated ( p < 0.05) in the CV-supplemented group compared to the control group. The alpha diversity indices (Chao1 and observed features) of the cecal microbiome in 10-day-old birds increased ( p < 0.05), indicating higher richness within the cecal bacterial community. In the microbiome analysis, enriched genera abundance of Clostridium ASF356 and Coriobacteriaceae CHKCI002 was observed in birds fed the diet containing CV compared to those fed the control diet. Taken together, dietary CV supplementation might alter intestinal barrier function, immunity, and microbiomes in 10-day-old broiler chickens.
Databáze: MEDLINE
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