Molecular Characterization of Staphylococcus aureus Complex Isolated from Free-Ranging Long-Tailed Macaques at Kosumpee Forest Park, Maha Sarakham, Thailand.

Autor:	Pumipuntu N; One Health Research Unit, Mahasarakham University, Maha Sarakham 44000, Thailand.; Veterinary Infectious Disease Research Unit, Mahasarakham University, Maha Sarakham 44000, Thailand.; Faculty of Veterinary Sciences, Mahasarakham University, Maha Sarakham 44000, Thailand., Tanee T; One Health Research Unit, Mahasarakham University, Maha Sarakham 44000, Thailand.; Faculty of Environment and Resource Studies, Mahasarakham University, Maha Sarakham 44150, Thailand., Thamsenanupap P; One Health Research Unit, Mahasarakham University, Maha Sarakham 44000, Thailand.; Faculty of Environment and Resource Studies, Mahasarakham University, Maha Sarakham 44150, Thailand., Kyes P; Department of Psychology, Center for Global Field Study and Washington National Primate Research Center, University of Washington, Seattle, WA 98195, USA., Karaket A; Department of National Parks, Wildlife and Plant Conservation, Bangkok 10900, Thailand., Kyes RC; Departments of Psychology, Global Health, Anthropology and Center for Global Field Study, Washington National Primate Research Center, University of Washington, Seattle, WA 98195, USA.
Jazyk:	angličtina
Zdroj:	Tropical medicine and infectious disease [Trop Med Infect Dis] 2023 Jul 20; Vol. 8 (7). Date of Electronic Publication: 2023 Jul 20.
DOI:	10.3390/tropicalmed8070374
Abstrakt:	The Staphylococcus ( S .) aureus complex, including methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA), and S. argenteus are bacterial pathogens that are responsible for both human and animal infection. However, insights into the molecular characteristics of MRSA, MSSA, and S. argenteus carriages in wildlife, especially in long-tailed macaques, rarely have been reported in Thailand. The objective of this study was to assess molecular characterization of MRSA, MSSA, and S. argenteus strains isolated from free-ranging long-tailed macaques ( Macaca fascicularis ) at Kosumpee Forest Park, Maha Sarakham, Thailand. A total of 21 secondary bacterial isolates (including 14 MRSA, 5 MSSA, and 2 S. argenteus ) obtained from the buccal mucosa of 17 macaques were analysed by a Polymerase chain reaction (PCR) to identify several virulence genes, including pvl , tst , hla , hlb clfA , spa (x-region), spa (IgG biding region), and coa . The most prevalent virulence genes were clfA , coa , and the spa IgG biding region which presented in all isolates. These data indicated that MRSA, MSSA, and S. argenteus isolates from the wild macaques at Kosumpee Forest Park possess a unique molecular profile, harbouring high numbers of virulence genes. These findings suggest that wild macaques may potentially serve as carriers for distribution of virulent staphylococcal bacteria in the study area. Competing Interests: The authors declare no conflicts of interest.
Databáze:	MEDLINE
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