The First Definition of Pulmonary Component of Hypereosinophilic Syndrome: Bronchial Casts.

Autor: Onay ZR; Department of Pediatric Pulmonology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey., Ayhan Y; Department of Pediatric Pulmonology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey., Can Oksay S; Department of Pediatric Pulmonology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey., Mavi D; Department of Pediatric Pulmonology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey., Bilgin G; Department of Pediatric Pulmonology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey., Toksoz Yıldırım A; Department of Pathology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey., Canbolat Ayhan A; Department of Pediatric Hematology and oncology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey This case was presented as oral presentation at the Turkish Thoracic Society 24th Annual Congress with International Participation (hybrid congress) in 2021 and was deemed worthy of the 'Lung Pathology Study Group Oral Presentation Award.', Girit S; Department of Pediatric Pulmonology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Thoracic research and practice [Thorac Res Pract] 2023 Jan; Vol. 24 (1), pp. 49-52.
DOI: 10.5152/ThoracResPract.2022.22064
Abstrakt: Hypereosinophilic syndrome is a heterogeneous disease characterized by eosinophilic tissue inflammation and eosinophilia. Pulmonary involvement could be seen in up to 55% among children with hypereosinophilic syndrome. A 3-year-old boy with chronic hypereosinophilia and respiratory complaints was diagnosed with idiopathic hypereosinophilic syndrome. Atelectasis was detected in the radiological evaluation, and bronchial casts with eosinophilic structures were removed by bronchoscopy. Steroid, inhaled hypertonic saline, inhaled bronchodilator, inhaled corticosteroid, and leukotriene receptor antagonist were used for 1 year in the management of hypereosinophilic syndrome, and related eosinophilic casts and repetitive bronchoscopies were administered for removal of the casts. The patient was successfully managed with an inhaled N-acetyl cysteine treatment. In children, the long-term prognosis of hypereosinophilic syndrome is uncertain. Comprehensive diagnostic tests are required for the early diagnosis and management of pediatric hypereosinophilic syndrome. In the presented case, the rare occurrence of pulmonary involvement of hypereosinophilic syndrome in a 3 year-old-boy with recurrent hypereosinophilic casts and its management were discussed.
Databáze: MEDLINE