Bactericidal role of epidermal mucus of freshwater fish treated with Aeromonas hydrophila.

Autor: Ali S; Laboratory of Fisheries and Aquaculture, Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan., Shah SAUR; Laboratory of Fisheries and Aquaculture, Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan., Rauf M; Laboratory of Fisheries and Aquaculture, Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan., Hassan M; Institute of System Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), Bangi, Selangor, Malaysia., Ullah W; Department of Microbiology, Kohat University of Science and Technology, Kohat, Pakistan., Dawar FU; Laboratory of Fisheries and Aquaculture, Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan.
Jazyk: angličtina
Zdroj: Journal of fish diseases [J Fish Dis] 2023 Nov; Vol. 46 (11), pp. 1225-1237. Date of Electronic Publication: 2023 Jul 27.
DOI: 10.1111/jfd.13841
Abstrakt: This study explored the bactericidal role of the epidermal mucus (EM) of five freshwater Cyprinid fish species namely Ctenopharyngodon idella, Labeo rohita, Catla catla, Hypophthalmichthys molitrix, and Cirrhinus mrigala after treatment with Aeromonas hydrophila. Extracts of EM (crude and acidic) of each species showed bactericidal activity against various Gram -ve (Pseudomonas aeruginosa, Escherichia coli, Aeromonas hydrophila, Edwardsiella tarda, Salmonella enterica, Klebsiella pneumonia, Serratia marcescens, and Enterobacter cloacae) and Gram +ve (Bacillus wiedmannii and Staphylococcus aureus) bacteria compared with standard antibiotics (Fosfomycin). The zone of inhibition (ZOI) was measured in millimetres against antibiotics (Fosfomycin). Variations in bactericidal activity of EM were observed against bacteria from the same and different fish species. The acidic extract was more effective than the crude extract and showed significantly higher ZOI values against various bacteria and Fosfomycin antibiotics. This result shows that fish EM may perform an important role in fish defence against bacteria. Therefore, this study may hint towards the substitution of synthetic antibiotics with fish EM that may be used as a novel 'bactericidal' in aquaculture as well as in humans against bacterial infections.
(© 2023 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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