[Effect of different delivery modes on the level of cortical hormones in cord artery and vein blood].

Autor:	Jin Z; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of human milk science, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Wang Y; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of human milk science, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Jiang S; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of human milk science, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Man Q; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of human milk science, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Yang X; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of human milk science, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Xing X; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of human milk science, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Li L; Beijing HAOSI Medical Laboratory Co. , Ltd, Beijing 100050, China., Shao L; Beijing HAOSI Medical Laboratory Co. , Ltd, Beijing 100050, China., Song Z; Beijing HAOSI Medical Laboratory Co. , Ltd, Beijing 100050, China., Dai N; People's Hospital of Danyang, Zhenjiang 212300, China., Lai J; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of human milk science, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Jazyk:	čínština
Zdroj:	Wei sheng yan jiu = Journal of hygiene research [Wei Sheng Yan Jiu] 2023 May; Vol. 52 (3), pp. 424-428.
DOI:	10.19813/j.cnki.weishengyanjiu.2023.03.015
Abstrakt:	Objective: To investigate the difference of cortical hormones in cord artery and vein blood of newborns with different delivery modes. Methods: A total of 65 pregnant women who delivered in the People's Hospital of Danyang City, Jiangsu Province from June to September 2021 were selected as the study subjects, including 26 cases of spontaneous delivery and 39 cases of cesarean section. The basic information of 65 pregnant women and newborns was collected by questionnaire survey. According to the mode of delivery, the levels of corticosteroids in umbilical vein and umbilical artery blood were determined by liquid chromatography-tandem mass spectrometry(LC-MS/MS), including corticosterone, 11-desoxycorticosterone, aldosterone, cortisol, 11-deoxycortisol and cortisone. The data were statistically analyzed using IBM SPSS Statistics 26.0 statistical software. Results: The levels of cortisol, 11-deoxycortisol, aldosterone, cortisol, 11-deoxycortisol and cortisone in the umbilical vein blood of the spontaneous delivery group were(2.44±1.87), (0.64±0.29), (0.49±0.35), (54.95±40.80), (3.20±1.23) and(142.27±57.42)ng/mL, respectively. The levels of corticosterone, 11-deoxycortisol, aldosterone, cortisol, 11-deoxycortisol and cortisone in umbilical artery blood were(4.51±4.47), (0.57±0.28), (0.42±0.29), (60.79±45.53), (2.69±1.25) and(123.10±46.32)ng/mL, respectively. The levels of corticosterone, 11-deoxycortisone, aldosterone, cortisol, 11-deoxycortisone and cortisone in umbilical vein blood of cesarean section group were(0.94±1.09), (0.47±0.14), (0.26±0.14), (22.63±19.82), (2.30±0.90) and(84.51±29.49)ng/mL, respectively. The levels of corticosterone, 11-deoxycortisol, aldosterone, cortisol, 11-deoxycortisol and cortisone in umbilical artery blood were(2.22±2.24), (0.43±0.17), (0.27±0.14), (30.09±25.93), (1.87±0.76) and(75.03±24.90)ng/mL, respectively. The levels of corticosterone, 11-desoxycorticosterone, aldosterone, cortisol, 11-deoxycortisol and cortisone in cord vein blood and cord artery blood in spontaneous labor group were significantly higher than those in cesarean section group(P<0.05). The levels of corticosterone and cortisol in cord vein blood were significantly lower in spontaneous labor group and cesarean section group than those in cord artery blood(P<0.05), the levels of 11-desoxycorticosterone, 11-deoxycortisol and cortisone in cord vein blood were significantly higher in spontaneous labor group and cesarean section group than those in cord artery blood(P<0.05). Conclusion: There are differences in the level of cortical hormones in cord artery and vein blood in different delivery modes.
Databáze:	MEDLINE
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