Prescription of oral antidiabetics in Mexico. A cross-sectional study.

Autor: Fierro I; Departamento de Ciencias de la Salud, Universidad Europea Miguel de Cervantes, Valladolid, Spain., Gallardo-Mora O; Programa de Maestría y Doctorado en Ciencias Médicas, Odontológicas y de la Salud, Universidad Nacional Autónoma de México (UNAM), Mexico, Mexico., Alba-Leonel A; Escuela Nacional de Enfermería y Obstetricia, Universidad Nacional Autónoma de México (UNAM), Mexico, Mexico., Carvajal A; Universidad de Valladolid, Valladolid, Spain., Molina-Guarneros JA; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico, Mexico.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Jul 27; Vol. 18 (7), pp. e0288699. Date of Electronic Publication: 2023 Jul 27 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0288699
Abstrakt: In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors associated with inappropriate prescription in Mexico. A retrospective cross-sectional drug utilization study has been conducted. A randomly selected sample was carefully examined. Out of 3600 clinical records of patients diagnosed with type 2 diabetes mellitus (T2DM), 196 records were revised. As far as control is concerned, 36.7% had their glycemia values in the recommended range. A combination of different antidiabetics was the most common pattern observed (60.7%); the most frequent was that of the association of metformin with whatever oral antidiabetics. Prescriptions were considered as inappropriate in 149 cases (76.0%); younger age and lack of nutritional assessment was significantly related to inappropriate prescription. A trend to use more drugs for treating T2DM has been consistently observed. Despite using so many drugs, most of the patients are not controlled. Avoiding inappropriate prescription by following current guidelines may contribute to a better control and, in turn, decrease morbidity and mortality for this cause.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2023 Fierro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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