[Survival in Copd Patients with Long-Term Oxygen Therapy].

Autor:	García García MDC; Hospital Universitario de Badajoz, Servicio de Neumología, Badajoz, España., Hernández Borge J; Hospital Universitario de Badajoz, Servicio de Neumología, Badajoz, España., García García GM; Hospital Universitario de Badajoz, Servicio de Medicina Interna, Badajoz, España., Márquez Pérez FL; Hospital Universitario de Badajoz, Servicio de Neumología, Badajoz, España.
Jazyk:	Spanish; Castilian
Zdroj:	Open respiratory archives [Open Respir Arch] 2021 Jul 28; Vol. 3 (4), pp. 100119. Date of Electronic Publication: 2021 Jul 28 (Print Publication: 2021).
DOI:	10.1016/j.opresp.2021.100119
Abstrakt:	Introduction: Continuous home oxygen therapy (CHOT), along with smoking cessation, is the first treatment that has been shown to increase the survival of patients with chronic obstructive pulmonary disease (COPD) and chronic hypoxemia. Objective: To determine survival in a cohort of COPD patients receiving CHOT and to analyze the main causes and risk factors associated with their mortality. Methods: Prospective study of a cohort of COPD patients receiving CHOT. Numerous variables, including survival and cause of death at the end of follow-up, were collected. Results: A total of 409 COPD patients receiving CHOT were included (85.6% men; mean age: 71.27 ± 9.74 years). Mean time of CHOT follow-up was 5.86 ± 3.24 years and median survival was 6 years (95% CI: 5.47-6.53). Mortality at the end of follow-up was 75.8%, the leading cause of death being respiratory (36.9%). Longer survival was significantly associated with lower age, correct CHOT compliance, absence of exacerbations in the previous year, use of long-acting anticholinergics (LAMA), less severe COPD, presence of sleep apnea-hypopnea syndrome/obesity hypoventilation syndrome (SAHS/SHO), absence of malignant disease, heart disease, cerebrovascular disease, and kidney disease. Conclusions: The survival of COPD patients receiving CHOT was very long. The main causes of mortality were respiratory (36.9%). Independent predictors of mortality were age, presence of exacerbations in the previous year, previous diagnosis of cancer, and presence of cerebrovascular and renal disease. (© 2021 Sociedad Española de Neumología y Cirugía Torácica (SEPAR). Published by Elsevier España, S.L.U.)
Databáze:	MEDLINE
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