Early intervention with double balloon enteroscopy for higher yield for inpatient overt obscure gastrointestinal bleeding: A propensity matched analysis.

Autor: Aryan M; Department of Internal Medicine University of Alabama at Birmingham Birmingham Alabama USA., Venkata KVR; Department of Internal Medicine University of Alabama at Birmingham Montgomery Montgomery Alabama USA., Colvin T; Department of Internal Medicine University of Alabama at Birmingham Birmingham Alabama USA., Daley L; Department of Internal Medicine University of Alabama at Birmingham Birmingham Alabama USA., Patel P; Department of Internal Medicine University of Alabama at Birmingham Birmingham Alabama USA., Beasley TM; Department of Veteran's Affairs Birmingham/Atlanta VA Geriatric Research, Education, & Clinical Center Birmingham Alabama USA.; Department of Biostatics University of Alabama at Birmingham Birmingham Alabama USA., Nunley B; Department of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama USA., Baldwin N; Department of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama USA., Ahmed AM; Department of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama USA., Kyanam Kabir Baig KR; Department of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama USA., Mönkemüller K; Gastroenterology Ameos Klinikum University Teaching Hospital Halberstadt Germany., Peter S; Department of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama USA.
Jazyk: angličtina
Zdroj: JGH open : an open access journal of gastroenterology and hepatology [JGH Open] 2023 Jul 17; Vol. 7 (7), pp. 509-515. Date of Electronic Publication: 2023 Jul 17 (Print Publication: 2023).
DOI: 10.1002/jgh3.12943
Abstrakt: Background and Aim: Overt obscure gastrointestinal bleeding (OOGIB) is defined as continued bleeding with unknown source despite esophagogastroduodenoscopy (EGD) and colonoscopy evaluation. Small bowel evaluation through video capsule endoscopy (VCE) or double balloon enteroscopy (DBE) is often warranted. We studied the timing of DBE in hospitalized OOGIB patients regarding diagnostic yield, therapeutic yield, and GI rebleeding.
Methods: We performed a retrospective review of DBEs performed at a tertiary medical center between November 2012 and December 2020. The inclusion criterion was first admission for OOGIB undergoing DBE. Those without previous EGD or colonoscopy were excluded. Patients were stratified into two groups: DBE performed within 72 h of OOGIB (emergent) and beyond 72 h of OOGIB (nonemergent). Propensity score matching was used to adjust for the difference in patients in the two groups. Logistic regression analysis was used to assess factors associated with diagnostic and therapeutic yield. Kaplan-Meir survival curve showed GI bleed-free survival following initial bleed and was compared using the log rank test.
Results: A total of 154 patients met the inclusion criterion, of which 62 had emergent DBE and 92 had nonemergent DBE. The propensity-score-matched sample consisted of 112 patients, with 56 patients each in the emergent and nonemergent groups. Univariate and multivariable logistic regression analysis showed a significant association between VCE and emergent DBE and diagnostic and therapeutic yield ( P  < 0.05). Emergent DBE patients had increased GI bleed-free survival compared to those in the nonemergent group ( P  = 0.009).
Conclusion: Our data demonstrate that emergent DBE during inpatient OOGIB can impact the overall diagnostic yield, therapeutic yield, and GI rebleeding post DBE.
(© 2023 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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