Curcumin Supplementation and Vascular Health: Is Gut Microbiota Involved?

Autor: Laudani S; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., Di Domenico FM; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., Paladino N; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., Guerrera I; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., Grosso G; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., Godos J; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Jazyk: angličtina
Zdroj: Current pharmaceutical design [Curr Pharm Des] 2023; Vol. 29 (25), pp. 1971-1974.
DOI: 10.2174/1381612829666230726112255
Abstrakt: Curcumin is a polyphenol compound widely investigated for its potential health benefits. Clinical evidence from randomized controlled trials shows substantial positive effects in healthy individuals but contrasting results for patients with cardio-metabolic disorders. There is growing evidence that the gut microbiota may play a role in curcumin transformation and absorption of more bioactive compounds, suggesting that the baseline health status (or other unmeasured variables) may explain the observed variability of the results.
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Databáze: MEDLINE