Race and sex differences in dropout from the STRRIDE trials.

Autor:	Collins KA; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, United States., Huffman KM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, United States.; Division of Rheumatology, Duke University School of Medicine, Durham, NC, United States., Wolever RQ; Department of Physical Medicine and Rehabilitation, Vanderbilt University School of Medicine, Nashville, TN, United States., Smith PJ; Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States., Siegler IC; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States., Ross LM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, United States.; Division of Cardiology, Duke University School of Medicine, Durham, NC, United States., Jakicic JM; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, United States., Costa PT; Department of Medicine, Division of Geriatrics, Duke University School of Medicine, Durham, NC, United States., Kraus WE; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, United States.; Division of Cardiology, Duke University School of Medicine, Durham, NC, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in sports and active living [Front Sports Act Living] 2023 Jul 10; Vol. 5, pp. 1215704. Date of Electronic Publication: 2023 Jul 10 (Print Publication: 2023).
DOI:	10.3389/fspor.2023.1215704
Abstrakt:	Purpose: To determine if race and sex differences exist in determinants and timing of dropout among individuals enrolled in an exercise and/or caloric restriction intervention. Methods: A total of 947 adults with dyslipidemia (STRRIDE I, STRRIDE AT/RT) or prediabetes (STRRIDE-PD) were randomized to either inactive control or to 1 of 10 exercise interventions, ranging from doses of 8-23 kcal/kg/week, intensities of 50%-75% V ˙ O 2 peak, and durations of 6-8 months. Two groups included resistance training, and one included a dietary intervention (7% weight loss goal). Dropout was defined as an individual withdrawn from the study, with the reasons for dropout aggregated into determinant categories. Timing of dropout was defined as the last session attended and aggregated into phases (i.e., "ramp" period to allow gradual adaptation to exercise prescription). Utilizing descriptive statistics, percentages were generated according to categories of determinants and timing of dropout to describe the proportion of individuals who fell within each category. Results: Black men and women were more likely to be lost to follow-up (Black men: 31.3% and Black women: 19.6%), or dropout due to work responsibilities (15.6% and 12.5%), "change of mind" (12.5% and 8.9%), transportation issues (6.3% and 3.6%), or reported lack of motivation (6.3% and 3.6%). Women in general noted lack of time more often than men as a reason for dropout (White women: 22.4% and Black women: 22.1%). Regardless of race and sex, most participants dropped out during the ramp period of the exercise intervention; with Black women (50%) and White men (37.1%) having the highest dropout rate during this period. Conclusion: These findings emphasize the importance of targeted retention strategies when aiming to address race and sex differences that exist in determinants and timing of dropout among individuals enrolled in an exercise and/or caloric restriction intervention. Competing Interests: JMJ is on the Scientific Advisory Board for Wondr Health, Inc.; he is a consultant for Education Initiatives, Inc.; and he is the principal investigator for a research contract provided to the University of Kansas Medical Center by Epitomee Medical, Inc. RQW is on the Scientific Advisory Board for Wondr Health, Inc.; she is a Consultant for Fullfill, Inc.; she is the principal investigatory for a contract between Meharry Medical College and Vanderbilt University Medical Center; and she is the principal investigator for a contract between Coalition for Better Health and Vanderbilt University Medical Center. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (© 2023 Collins, Huffman, Wolever, Smith, Siegler, Ross, Jakicic, Costa and Kraus.)
Databáze:	MEDLINE
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