Impact of obstructive sleep apnea in cardiovascular risk in the pediatric population: A systematic review.

Autor: Castillo-García M; Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain; Predoctoral Student in Universidad de Alcalá, Madrid, Spain; Sleep Research Institute, Madrid, Spain., Solano-Pérez E; Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Coso C; Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Romero-Peralta S; Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain; Predoctoral Student in Universidad de Alcalá, Madrid, Spain; Sleep Research Institute, Madrid, Spain., García-Borreguero D; Sleep Research Institute, Madrid, Spain., Izquierdo JL; Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain; Medicine Department, Universidad de Alcalá, Madrid, Spain., Mediano O; Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain; Medicine Department, Universidad de Alcalá, Madrid, Spain. Electronic address: olgamediano@hotmail.com.
Jazyk: angličtina
Zdroj: Sleep medicine reviews [Sleep Med Rev] 2023 Oct; Vol. 71, pp. 101818. Date of Electronic Publication: 2023 Jul 13.
DOI: 10.1016/j.smrv.2023.101818
Abstrakt: While the association of obstructive sleep apnea (OSA) with an increased cardiovascular risk (CVR) in the adult population is well known, there is insufficient evidence to affirm something similar in the pediatric population. On the other hand, adenotonsillectomy has been shown to be an effective treatment. Our objective was to evaluate the association of sleep respiratory disorders in children with increased CVR and the impact of adenotonsillectomy in the literature. To this aim, a literature search was conducted, between 2002 to the present. After carrying out a systematic review, the following results were provided: thoracic echocardiography after surgery found improvements in terms of cardiac function and structure; blood pressure (BP) measurement, verified a tendency to higher BP values in the OSA pediatric population, which improved after surgery; different biomarkers of CVR, were increased in OSA patients and improved after treatment and finally; some studies found endothelial dysfunction in pediatric OSA, a measurement of vascular system function, was reversible with adenotonsillectomy. Increases in BP parameters, biological markers related to CVR and alterations in cardiac function structure, have been reported in pediatric patients with OSA. At least, some of these parameters would be reversible after adenotonsillectomy, reflecting a possible reduction in CVR.
Competing Interests: Declaration of competing interest Diego García-Borreguero declares have collaborated with Roche and Idorsia.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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