The impact of module dosage on treatment response in a modular transdiagnostic intervention for sleep and circadian dysfunction (TranS-C).

Autor: Callaway CA; University of California, Berkeley, United States., Sarfan LD; University of California, Berkeley, United States., Gumport NB; Stanford University, United States., Harvey AG; University of California, Berkeley, United States. Electronic address: aharvey@berkeley.edu.
Jazyk: angličtina
Zdroj: Behaviour research and therapy [Behav Res Ther] 2023 Sep; Vol. 168, pp. 104368. Date of Electronic Publication: 2023 Jul 05.
DOI: 10.1016/j.brat.2023.104368
Abstrakt: The efficacy of modular evidence-based psychological treatments is promising, yet variation in module delivery is understudied. This study evaluated module delivery of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) and its impact on patient outcomes. Adults (N = 108) with serious mental illness and sleep and circadian dysfunction treated in a community setting were randomized to receive TranS-C plus usual care, or 6 months of usual care followed by delayed treatment with TranS-C. Data from both conditions were combined to maximize power. These secondary analyses tested whether the "dosage" of module delivery (defined as the proportion of total sessions in which a module was delivered) predicted treatment response, measured as functional impairment, psychiatric symptoms, sleep and circadian dysfunction, and sleep health, at post-treatment and 6-month follow-up. Higher dosages of seven modules were associated with improvement in the outcome variables (βs = -0.11-0.44; ps = 0.000-0.030). Higher dosages of three modules were associated with a worsening of one or two outcome variables (βs = 0.22-0.29; ps = 0.001-0.043). Higher dosages of the remaining modules were not associated with outcomes. Although more evidence is needed, it may be wise to consider focusing provider trainings on ensuring fidelity to certain modules, given limited training time in community settings. ClinicalTrials.gov Identifier: NCT02469233, registered June 9, 2015.
Competing Interests: Declaration of competing interest Allison G. Harvey has received research support from the National Institutes of Health and book royalties from American Psychological Association, Guilford Press, and Oxford University Press. Catherine A. Callaway, Laurel D. Sarfan, and Nicole B. Gumport have received research support from the National Institutes of Health. All other authors declare that they have no competing interests.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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