Multidrug resistance in pathogens of community-acquired urinary tract infections in Turkey: a multicentre prospective observational study

Autor:	Şencan İ; Department of Infectious Diseases and Clinical Microbiology, Dışkapı Yıldırım Beyazıt Training and Research Hospital, University of Health Sciences, Ankara, Turkey., Karabay O; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey., Altay FA; Department of Infectious Diseases and Clinical Microbiology Faculty of Medicine, Lokman Hekim University, Ankara, Turkey., Yıldız SS; Department of Microbiology Reference Laboratory and Biological Products, General Directorate of Public Health, Republic of Turkey Ministry of Health , Ankara, Turkey., Şimşek H; Department of Microbiology Reference Laboratory and Biological Products, General Directorate of Public Health, Republic of Turkey Ministry of Health , Ankara, Turkey., Gözükara MG; Department of Communicable Diseases, Ankara Sincan Provincial Health Directorate, Republic of Turkey Ministry of Health, Ankara, Turkey., Kuzi S; Department of Infectious Diseases and Clinical Microbiology, Ünye State Hospital, Republic of Turkey Ministry of Health, Ordu, Turkey., Karlıdağ GE; Department of Infectious Diseases and Clinical Microbiology, Fethi Sekin City Hospital, University of Health Sciences, Elazığ, Turkey., Kaya Ş; Department of Infectious Diseases and Clinical Microbiology, Gazi Yaşargil Research and Training Hospital, University of Health Sciences, Diyarbakır, Turkey., Kul G; Department of Infectious Diseases and Clinical Microbiology, Kırıkhan State Hospital, Republic of Turkey Ministry of Health, Hatay, Turkey., Türkoğlu E; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Gaziosmanpaşa University, Tokat, Turkey., Sezer BE; Department of Infectious Diseases and Clinical Microbiology, Çorlu State Hospital, Republic of Turkey Ministry of Health, Tekirdağ, Turkey., Korkmaz N; Department of Infectious Diseases and Clinical Microbiology, Kahramankazan State Hospital, Republic of Turkey Ministry of Health, Ankara, Turkey., Kaya SY; Department of Infectious Diseases and Clinical Microbiology, Sungurlu State Hospital, Republic of Turkey Ministry of Health, Çorum, Turkey., Sayar MS; Department of Infectious Diseases and Clinical Microbiology, Van Research and Training Hospital, Republic of Turkey Ministry of Health, Van, Turkey., Bulut D; Department of Infectious Diseases and Clinical Microbiology, Dışkapı Yıldırım Beyazıt Training and Research Hospital, University of Health Sciences, Ankara, Turkey., Akgül F; Department of Infectious Diseases and Clinical Microbiology, Batman Research and Training Hospital, Republic of Turkey Ministry of Health, Batman, Turkey., Çağ Y; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, İstanbul Medeniyet University, İstanbul, Turkey Fenerbahçe University, İstanbul, Turkey., Ağalar C; Department of Infectious Diseases, Fenerbahçe University, İstanbul, Turkey., Dursun ZB; Department of Infectious Diseases and Clinical Microbiology, Kayseri Medicine Faculty, University of Health Sciences, Kayseri, Turkey., Taşbakan M; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkey., Aydemir SŞ; Department of Microbiology and Clinical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkey., Seyman D; Department of Infectious Diseases and Clinical Microbiology, Antalya Education and Research Hospital, University of Health Sciences, Antalya, Turkey., Yıldırım M; Department of Infectious Diseases and Microbiology, İstanbul Training and Research Hospital, University of Health Sciences, İstanbul, Turkey., Habip Z; Department of Medical Microbiology, Faculty of Medicine, İstanbul Medeniyet University, İstanbul, Turkey., Altın N; Department of Infectious Diseases and Clinical Microbiology, Dışkapı Yıldırım Beyazıt Training and Research Hospital, University of Health Sciences, Ankara, Turkey., Uzar H; Department of Infectious Diseases and Clinical Microbiology, Viranşehir State Hospital, Republic of Turkey Ministry of Health, Şanlıurfa, Turkey., Bektaş B; Department of Infectious Diseases and Clinical Microbiology, Sancaktepe İlhan Varank Training and Research Hospital, Republic of Turkey Ministry of Health, İstanbul, Turkey., Engin DÖ; Department of Infectious Diseases and Clinical Microbiology, Sancaktepe İlhan Varank Training and Research Hospital, Republic of Turkey Ministry of Health, İstanbul, Turkey., Erdem HA; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkey., Sürme S; Department of Infectious Diseases and Clinical Microbiology, Haseki Training and Research Hospital, Republic of Turkey Ministry of Health, İstanbul, Turkey ; Department of Medical Microbiology, Institute of Graduate Studies, İstanbul University-Cerrahpasa, İstanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Turkish journal of medical sciences [Turk J Med Sci] 2023 Jun; Vol. 53 (3), pp. 780-790. Date of Electronic Publication: 2023 Jun 19.
DOI:	10.55730/1300-0144.5641
Abstrakt:	Background: To have country-wide information about multidrug resistance (MDR) in isolates from community-acquired urinary tract infections (CAUTI) of Turkey, in terms of resistance rates and useful options. Methods: We used a geocode standard, nomenclature of territorial units for statistics (NUTS), and a total of 1588 community-acquired isolates of 20 centres from 12 different NUTS regions between March 2019 and March 2020 were analysed. Results: Of the 1588 culture growths, 1269 (79. 9%) were Escherichia coli and 152 (9.6%) were Klebsiella spp. Male sex, advancedage, and having two or more risk factors showed a statistically significant relation with MDR existence (p < 0.001, p: 0.014, p < 0.001, respectively) that increasing number of risk factors or degree of advancing in age directly affects the number of antibiotic groups detected to have resistance by pathogens. In total, MDR isolates corresponded to 36.1% of our CAUTI samples; MDR existence was 35.7% in E. coli isolates and 57.2% in Klebsiella spp. isolates. Our results did not show an association between resistance or MDR occurrence rates and NUTS regions. Discussion: The necessity of urine culture in outpatient clinics should be taken into consideration, at least after evaluating risk factorsfor antibacterial resistance individually. Community-acquired UTIs should be followed up time- and region-dependently. Antibiotic stewardship programmes should be more widely and effectively administrated.
Databáze:	MEDLINE
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