Psychotic-like experiences and multimorbid psychopathology: The relationship between the 16-item prodromal questionnaire and DSM-IV classifications in a help-seeking population.

Autor: Palstra EC; Department of Clinical Psychology, VU University and Amsterdam Public Health Research, Amsterdam, The Netherlands.; Department of Psychosis Research, Parnassia Academy, The Hague, The Netherlands., Ferwerda J; Mental Healthcare Organisation GGZ Noord-Holland-Noord, Heerhugowaard, The Netherlands., van Duin EDA; Department of Clinical Psychology, VU University and Amsterdam Public Health Research, Amsterdam, The Netherlands.; Department of Psychosis Research, Parnassia Academy, The Hague, The Netherlands., Ising HK; GGZ Rivierduinen Academy, Leiden, The Netherlands., Nugter MA; Department of Research and Care Evaluation, Mental Healthcare Organisation GGZ Noord-Holland-Noord, Heerhugowaard, The Netherlands., Smit F; Department of Mental Health Prevention, Trimbos Institute, Utrecht, The Netherlands.; Department of Epidemiology and Biostatistics, Amsterdam University Medical Centres, Amsterdam, The Netherlands., van der Gaag M; Department of Clinical Psychology, VU University and Amsterdam Public Health Research, Amsterdam, The Netherlands.; Department of Psychosis Research, Parnassia Academy, The Hague, The Netherlands., van den Berg D; Department of Clinical Psychology, VU University and Amsterdam Public Health Research, Amsterdam, The Netherlands.; Department of Psychosis Research, Parnassia Academy, The Hague, The Netherlands.
Jazyk: angličtina
Zdroj: Early intervention in psychiatry [Early Interv Psychiatry] 2024 Mar; Vol. 18 (3), pp. 217-225. Date of Electronic Publication: 2023 Jul 20.
DOI: 10.1111/eip.13454
Abstrakt: Aim: Identifying multimorbid psychopathology is necessary to offer more adequate treatment and ultimately reduce the prevalence of persistent mental illnesses. Psychotic symptoms are increasingly seen as a transdiagnostic indicator of multimorbidity, severity and complexity of non-psychotic psychopathology. This study aims to investigate whether psychotic-like experiences and subclinical psychotic symptoms as measured by the 16-item Prodromal Questionnaire are also associated with multimorbid psychopathology.
Methods: Participants were help-seeking individuals from outpatient mental healthcare settings and intensive home-treatment teams, aged 17-35. Assessment included the 16-item Prodromal Questionnaire to measure psychotic-like experiences, the Structured Clinical Interview for DSM-IV Axis I, and three sections of the Structured Clinical Interview for DSM-IV Axis II Disorders to determine DSM-IV-TR classifications. The final sample comprised of 160 participants who scored above a cutoff of 6 items on the 16-item Prodromal Questionnaire (HIGH-score) and 60 participants who scored below cutoff (LOW-score). A Poisson Regression was executed to determine the association between the PQ-16 and DSM-IV-TR classifications.
Results: The HIGH-score group had a mean of 2.76 multimorbid disorders (range 0-7), while the LOW-score group had a mean of 1.45 disorders (range 0-3). Participants with four to seven disorders scored high on the 16-item Prodromal Questionnaire.
Conclusions: Our results suggest that psychotic-like experiences are associated with multimorbidity and severity of psychopathology. Screening for psychotic-like experiences via the PQ-16 in a help-seeking population may help prevent under-diagnosis and under-treatment of comorbid psychopathology.
(© 2023 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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