Performance evaluation of Monaco radiotherapy treatment planning system using CIRS Thorax Phantom: Dosimetric assessment of flattened and non-flattened photon beams.

Autor: Saini A; Department of Medical Physics, Tata Memorial Center, Homi Bhabha Cancer Hospital, Sangrur, Punjab; Chitkara University Institute of Engineering and Technology, Chitkara University, Punjab, India., Verma T; Department of Radiotherapy, King George Medical University, Lucknow, Uttar Pradesh, India., Pandey VP; Department of Medical Physics, Hind Institute of Medical Sciences, Safedabad, Barabanki, Uttar Pradesh, India., Singh A; Department of Medical Physics, Tata Memorial Center, Homi Bhabha Cancer Hospital, Sangrur, Punjab; Chitkara University Institute of Engineering and Technology, Chitkara University, Punjab, India., Kumar P; Chitkara University Institute of Engineering and Technology; Centre for Liquid Crystal Research, Chitkara University Research and Innovation Network, Chitkara University, Punjab, India.
Jazyk: angličtina
Zdroj: Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Apr-Jun; Vol. 19 (3), pp. 793-800.
DOI: 10.4103/jcrt.jcrt_967_21
Abstrakt: Aim: The present study was undertaken to evaluate the performance of different algorithms for flattening filter-free (FFF) and flattened (FF) photon beams in three different in-homogeneities.
Materials and Method: Computed tomography (CT) image sets of the CIRS phantom maintained in the SAD setup by placing the ionization chamber in the lung, bone, and tissue regions, respectively, were acquired. The treatment planning system (TPS) calculated and the ionization chamber measured the doses at the center of the chamber (in the three mediums) were recorded for the flattened and non-flattened photon beams.
Results: The results were reported for photon energies of 6 MV, 10 MV, 15 MV, 6 FFF, and 10 FFF of field sizes 5 × 5 cm 2 , 10 × 10 cm 2 , and 15 × 15 cm 2 . In the bone inhomogeneity, the pencil beam algorithm predicted that the maximum dose variation was 4.88% of measured chamber dose in 10-MV photon energy for the field size 10 × 10 cm 2 . In water inhomogeneity, both the collapsed cone and Monte Carlo algorithm predicted that the maximum dose variation was ± 3% of measured chamber dose in 10-MV photon energy for the field size 10 × 10 cm 2 and in 10-MV FFF photon energy for the field size 5 × 5 cm 2 , whereas in lung inhomogeneity, the pencil beam algorithm predicted that the highest dose variation was - 6.9% of measured chamber dose in 10-MV FFF photon energy for the field size 5 × 5 cm 2 .
Conclusion: FF and FFF beams performed differently in lung, water, and bone mediums. The assessment of algorithms was conducted using the anthropomorphic phantom; therefore, these findings may help in the selection of appropriate algorithms for particular clinical settings in radiation delivery.
Databáze: MEDLINE
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