Tmax volume can predict clinical type in patients with acute ischemic stroke.

Autor: Kishi F; Department of Neurosurgery, Yagi Neurosurgical Hospital, Higashinariku, Osaka, Japan., Nakagawa I; Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan., Kimura S; Department of Neurosurgery, Yagi Neurosurgical Hospital, Higashinariku, Osaka, Japan., Ogawa D; Department of Neurosurgery, Yagi Neurosurgical Hospital, Higashinariku, Osaka, Japan., Yagi R; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Yamada K; Department of Neurosurgery, Yagi Neurosurgical Hospital, Higashinariku, Osaka, Japan., Taniguchi H; Department of Neurosurgery, Yagi Neurosurgical Hospital, Higashinariku, Osaka, Japan.
Jazyk: angličtina
Zdroj: Brain and behavior [Brain Behav] 2023 Aug; Vol. 13 (8), pp. e3163. Date of Electronic Publication: 2023 Jul 20.
DOI: 10.1002/brb3.3163
Abstrakt: Objective: Endovascular therapy (EVT) is performed for acute ischemic stroke (AIS) with large vessel occlusion (LVO), however, the treatment strategies and clinical outcomes differ between cardiac embolism (CE) and intracranial arteriosclerosis-derived LVO (ICAS-LVO). We analyzed whether the time-to-max (Tmax) volume derived from perfusion imaging predicted clinical classification in AIS patients before EVT.
Methods: Consecutive AIS patients with anterior circulation LVO evaluated by automated imaging software were retrospectively identified. Patients were classified into a CE group and an ICAS-LVO group, and parameters were compared between groups.
Results: Thirty-nine patients were included and Tmax volume and Tmax > 6 s volume/Tmax > 4 s volume were significantly greater in the CE group than in the ICAS-LVO group (Tmax > 4 s volume: 261 mL vs. 149 mL, p = .01, Tmax > 6 s volume: 143 mL vs. 59 mL, p = .001, Tmax > 6 s volume/Tmax > 4 s volume: 0.59 vs. 0.40, p < .001). Multiple logistic regression analysis indicated an association between clinical classification and high Tmax > 6 s volume/Tmax > 4 s volume (p = .04).
Conclusion: The Tmax volume derived from perfusion imaging predicts the clinical classification of AIS patients before EVT.
(© 2023 The Authors. Brain and Behavior published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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