Tacrolimus-Induced Akinetic Mutism or Epidural Catheter Migration: A Case Report.

Autor: Hussey PT; From the Department of Anesthesiology and Perioperative Medicine., Sowell J; Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama., Hussey H; From the Department of Anesthesiology and Perioperative Medicine., Townsley MM; From the Department of Anesthesiology and Perioperative Medicine.
Jazyk: angličtina
Zdroj: A&A practice [A A Pract] 2023 Jul 18; Vol. 17 (7), pp. e01699. Date of Electronic Publication: 2023 Jul 18 (Print Publication: 2023).
DOI: 10.1213/XAA.0000000000001699
Abstrakt: Differential diagnosis of the underlying cause of new-onset total body paralysis can be challenging and unsatisfying. In akinetic mutism, a rare side effect of tacrolimus, patients become apathetic, mute, and lose voluntary muscle movement. Epidural subarachnoid migration can present with similar symptoms. Delayed emergence/paralysis after anesthesia can include the common culprits of residual operative medications, stroke, as well as tacrolimus-induced akinetic mutism and thoracic epidural migration. We present a case of new-onset total body paralysis, presenting on postoperative day 1 following a double-lung transplant in a patient started on tacrolimus with a thoracic epidural catheter in place.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2023 International Anesthesia Research Society.)
Databáze: MEDLINE