Tacrolimus-Induced Akinetic Mutism or Epidural Catheter Migration: A Case Report.
Autor: | Hussey PT; From the Department of Anesthesiology and Perioperative Medicine., Sowell J; Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama., Hussey H; From the Department of Anesthesiology and Perioperative Medicine., Townsley MM; From the Department of Anesthesiology and Perioperative Medicine. |
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Jazyk: | angličtina |
Zdroj: | A&A practice [A A Pract] 2023 Jul 18; Vol. 17 (7), pp. e01699. Date of Electronic Publication: 2023 Jul 18 (Print Publication: 2023). |
DOI: | 10.1213/XAA.0000000000001699 |
Abstrakt: | Differential diagnosis of the underlying cause of new-onset total body paralysis can be challenging and unsatisfying. In akinetic mutism, a rare side effect of tacrolimus, patients become apathetic, mute, and lose voluntary muscle movement. Epidural subarachnoid migration can present with similar symptoms. Delayed emergence/paralysis after anesthesia can include the common culprits of residual operative medications, stroke, as well as tacrolimus-induced akinetic mutism and thoracic epidural migration. We present a case of new-onset total body paralysis, presenting on postoperative day 1 following a double-lung transplant in a patient started on tacrolimus with a thoracic epidural catheter in place. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2023 International Anesthesia Research Society.) |
Databáze: | MEDLINE |
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