Social determinants of sex disparities in cancer in Southeast Asia.

Autor:	Arevalo MVPN; College of Medicine, University of the Philippines, 1000 Manila, Philippines., Maslog EAS; College of Medicine, University of the Philippines, 1000 Manila, Philippines., Manlongat KD; PGSP-Stanford Psy.D. Consortium, Palo Alto, CA, USA., Ornos EDB; College of Medicine, University of the Philippines, 1000 Manila, Philippines., Chitapanarux I; Division of Radiation Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Eala MAB; College of Medicine, University of the Philippines, 1000 Manila, Philippines.; Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA., Dee EC; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jazyk:	angličtina
Zdroj:	IScience [iScience] 2023 Jun 14; Vol. 26 (7), pp. 107110. Date of Electronic Publication: 2023 Jun 14 (Print Publication: 2023).
DOI:	10.1016/j.isci.2023.107110
Abstrakt:	Sex disparities in cancer exist along the cancer spectrum, ranging from genomic predisposition and behavioral risk factors to access to screening, diagnostics, treatment, and survivorship care. A growing body of research is studying the biological underpinnings of these differences, from cancer risk to tumor biology to treatment response. It is well known, however, that the social determinants of health play a large role across the cancer disease continuum, which encompasses risk, prevention, diagnosis, treatment, survivorship, rehabilitation, and palliative care. Less literature focuses on the gendered disparities that are epidemiologic in nature, especially in Southeast Asia (SEA), a diverse region that is home to nearly 670 million people, where most are lower middle income countries, and where socioeconomic and cultural factors increase cancer risk for women. In this review, we highlight the social drivers of gendered disparities, namely the geographic, environmental, sociocultural, economic, and political forces that contribute to the increased mortality and poorer health outcomes in the region. Competing Interests: Author disclosures. ECD is funded in part through the Cancer Center Support Grant from the National Cancer Institute (P30 CA008748). All other authors declare no competing interests. (© 2023 The Author(s).)
Databáze:	MEDLINE
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