Peripheral Insulin Edema and Pericardial Effusion in a 12-Year-Old Newly Diagnosed Girl with Type 1 Diabetes.

Autor: Janchevska A; 1University Children's Hospital, Skopje, RN Macedonia.; 2Medical Faculty, Skopje, RN Macedonia., Jovanovska V; 1University Children's Hospital, Skopje, RN Macedonia.; 2Medical Faculty, Skopje, RN Macedonia., Jordanova O; 1University Children's Hospital, Skopje, RN Macedonia.; 2Medical Faculty, Skopje, RN Macedonia., Beqiri-Jashari A; 1University Children's Hospital, Skopje, RN Macedonia.; 2Medical Faculty, Skopje, RN Macedonia., Krstevska-Konstantinova M; 1University Children's Hospital, Skopje, RN Macedonia.; 2Medical Faculty, Skopje, RN Macedonia., Tasic V; 1University Children's Hospital, Skopje, RN Macedonia.; 2Medical Faculty, Skopje, RN Macedonia., Gucev ZS; 1University Children's Hospital, Skopje, RN Macedonia.; 2Medical Faculty, Skopje, RN Macedonia.
Jazyk: angličtina
Zdroj: Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) [Pril (Makedon Akad Nauk Umet Odd Med Nauki)] 2023 Jul 15; Vol. 44 (2), pp. 171-174. Date of Electronic Publication: 2023 Jul 15 (Print Publication: 2023).
DOI: 10.2478/prilozi-2023-0037
Abstrakt: Introduction : Insulin induced edema (IIE) is a rare condition, usually found in newly diagnosed diabetes patients, either after insulin treatment initiation or after dose increment. It is a self-limited process, rarely associated with serosal effusions. Teenage girls with type 1 diabetes (T1DM) are most commonly affected. Patient and Methods : A 12-year-old girl was diagnosed with ketoacidosis (DKA). Seven days after initiation of the insulin treatment, at a stable total daily dose of insulin (TDDI) of 0.55 IU/kg, she came with two kilograms weight gain in only two days and edema of the feet and calves. Ultrasound of the heart found a 7 mm pericardial effusion. The diagnostic workout included clinical examination, biochemical, hormonal, allergen analyses and imaging which excluded other known causes of swelling. Conclusions : We describe an adolescent girl with newly diagnosed T1DM and a rare association of peripheral insulin-induced edema and pericardial effusion. Short-term diuretic treatment and salt restriction resolved this rare complication of insulin treatment.
(© 2023 Aleksandra Janchevska et al., published by Sciendo.)
Databáze: MEDLINE
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