Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors.

Autor: Skalsky K; Department of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Shiyovich A; Department of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Hochwald N; Department of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Levi A; Department of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Zreik L; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Imaging, Rabin Medical Center, Petach-Tikva 4941492, Israel., Tamir S; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Imaging, Rabin Medical Center, Petach-Tikva 4941492, Israel., Shafir G; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Imaging, Rabin Medical Center, Petach-Tikva 4941492, Israel., Briger A; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Organ Transplantation, Rabin Medical Center, Petach-Tikva 4941492, Israel., Rahamimov R; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Nephrology, Rabin Medical Center, Petach-Tikva 4941492, Israel., Kornowski R; Department of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Hamdan A; Department of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2023 Jul 07; Vol. 12 (13). Date of Electronic Publication: 2023 Jul 07.
DOI: 10.3390/jcm12134541
Abstrakt: Background: A unique scanning protocol combining coronary computed tomography angiography (CTA) with routine abdominal CTA is being used at the Rabin Medical Center as a method of screening high-risk candidates for living kidney donation. We aim to evaluate the potential impact of coronary CTA on the decision regarding eligibility for kidney donation and its correlation with abdominal aortic calcification (AAC).
Methods: CCTA and abdominal CTA results of potential living kidney donors evaluated for donation between September 2020 and November 2021 were retrieved. A retrospective analysis of the abdominal CTA was used to calculate the AAC. Patients' demographic, clinical, and imaging data were collected from the electronic files, as well as the final decision regarding eligibility for donation.
Results: A total of 62 potential kidney donors were evaluated for donation using the combined scan. The mean age was 53.8 years, with male predominance (59.7%). Significant coronary artery stenosis (≥70% luminal stenosis) was present in two patients (3.2%), whereas five patients (8%) had moderate stenosis (50-69%). Thirteen patients (21%) were disqualified from donation due to moderate-to-significant coronary artery disease or abdominal atherosclerosis. The correlation between the coronary artery calcium score and the AAC was found to be positive, with a Pearson correlation coefficient of 0.88 ( p < 0.001).
Conclusions: The use of coronary CTA in the evaluation of potential kidney donors may has a potential impact on the decision regarding eligibility for donation. A high correlation between the coronary artery calcium score and the AAC was found.
Databáze: MEDLINE
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