Maxillary Sinus Augmentation Using Autologous Platelet Concentrates (Platelet-Rich Plasma, Platelet-Rich Fibrin, and Concentrated Growth Factor) Combined with Bone Graft: A Systematic Review.

Autor: Malcangi G; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Patano A; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Palmieri G; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Di Pede C; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Latini G; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Inchingolo AD; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Hazballa D; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., de Ruvo E; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Garofoli G; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Inchingolo F; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Dipalma G; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy., Minetti E; Department of Biomedical, Surgical, Dental Science, University of Milan, 20161 Milan, Italy., Inchingolo AM; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy.
Jazyk: angličtina
Zdroj: Cells [Cells] 2023 Jul 06; Vol. 12 (13). Date of Electronic Publication: 2023 Jul 06.
DOI: 10.3390/cells12131797
Abstrakt: Background: The current review aims to provide an overview of the most recent research on the potentials of concentrated growth factors used in the maxillary sinus lift technique.
Materials and Methods: "PRP", "PRF", "L-PRF", "CGF", "oral surgery", "sticky bone", "sinus lift" were the search terms utilized in the databases Scopus, Web of Science, and Pubmed, with the Boolean operator "AND" and "OR".
Results: Of these 1534 studies, 22 publications were included for this review.
Discussion: The autologous growth factors released from platelet concentrates can help to promote bone remodeling and cell proliferation, and the application of platelet concentrates appears to reduce the amount of autologous bone required during regenerative surgery. Many authors agree that growth factors considerably enhance early vascularization in bone grafts and have a significantly positive pro-angiogenic influence in vivo when combined with alloplastic and xenogeneic materials, reducing inflammation and postoperative pain and stimulating the regeneration of injured tissues and accelerating their healing.
Conclusions: Even if further studies are still needed, the use of autologous platelet concentrates can improve clinical results where a large elevation of the sinus is needed by improving bone height, thickness and vascularization of surgical sites, and post-operative healing.
Databáze: MEDLINE
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