Continuous Glucose Monitoring in Transient Neonatal Diabetes Mellitus-2 Case Reports and Literature Review.

Autor: Chisnoiu T; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Balasa AL; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Mihai L; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Lupu A; Pediatrics, 'Grigore T. Popa', Department of Mother and Child Medicine, University of Medicine and Pharmacy, 700115 Iasi, Romania., Frecus CE; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Ion I; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Andrusca A; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Pantazi AC; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Nicolae M; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Lupu VV; Pediatrics, 'Grigore T. Popa', Department of Mother and Child Medicine, University of Medicine and Pharmacy, 700115 Iasi, Romania., Ionescu C; Department 1 Preclinical, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania., Mihai CM; Department of Pediatrics, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.; Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania., Cambrea SC; Department of Infectious Diseases, Faculty of General Medicine, 'Ovidius' University, 900470 Constanta, Romania.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2023 Jul 04; Vol. 13 (13). Date of Electronic Publication: 2023 Jul 04.
DOI: 10.3390/diagnostics13132271
Abstrakt: Neonatal diabetes mellitus is a rare genetic disease that affects 1 in 90,000 live births. The start of the disease is often before the baby is 6 months old, with rare cases of onset between 6 months and 1 year. It is characterized by low or absent insulin levels in the blood, leading to severe hyperglycemia in the patient, which requires temporary insulin therapy in around 50% of cases or permanent insulin therapy in other cases. Two major processes involved in diabetes mellitus are a deformed pancreas with altered insulin-secreting cell development and/or survival or faulty functioning of the existing pancreatic beta cell. We will discuss the cases of two preterm girls with neonatal diabetes mellitus in this research. In addition to reviewing the literature on the topic, we examined the different mutations, patient care, and clinical outcomes both before and after insulin treatment.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje