| Autor: |
Borgheresi A; Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy.; Department of Radiological Sciences, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy., Agostini A; Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy.; Department of Radiological Sciences, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy., Sternardi F; Department of Radiological Sciences, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy., Cesari E; Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy., Ventura F; Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy., Ottaviani L; Department of Radiological Sciences, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy., Delle Fave RF; Division of Urology, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy., Pretore E; Division of Urology, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy., Cimadamore A; Division of Pathology, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy.; Department of Biomedical Sciences and Public Healthcare, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy., Filosa A; Division of Pathology, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy.; Department of Biomedical Sciences and Public Healthcare, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy., Galosi AB; Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy.; Division of Urology, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy., Giovagnoni A; Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto 10, 60126 Ancona, Italy.; Department of Radiological Sciences, Azienda Ospedaliero Universitaria delle Marche, Via Conca 71, 60126 Ancona, Italy. |
| Abstrakt: |
In bladder cancer (BC), the evaluation of lymph node (LN) involvement at preoperative imaging lacks specificity. Since neoangiogenesis is paired with lymphatic involvement, this study aims to evaluate the presence of perivesical venous ectasia as an indirect sign of LN involvement, together with other conventional CT findings. All the patients who underwent radical cystectomy (RC) for BC between January 2017 and December 2019 with available preoperative contrast-enhanced CT (CECT) within 1 month before surgery were included. Patients without available pathological reports (and pTNM stage) or who underwent neoadjuvant treatments and palliative RC were excluded. Two readers in blind assessed the nodal shape and hilum, the short axis, and the contrast enhancement of suspicious pelvic LNs, the Largest Venous Diameter (LVD) efferent to the lesion, and the extravesical tumor invasion. In total, 38 patients (33 males) were included: 17 pT2, 17 pT3, 4 pT4; pN+: 20/38. LN short axis > 5 mm, LN enhancement, and LVD > 3 mm were significantly correlated with N+ at pathology. LVD > 3 mm had a significantly higher sensitivity and specificity (≥90%, AUC = 0.949) and was an independent predictor ( p = 0.0016). |
