Update on iodine-refractory differentiated thyroid carcinoma.

Autor: Abou Jokh Casas E; Servicio de Medicina Nuclear del Hospital Universitario Lucus Augusti, Lugo, Spain. Electronic address: estephanyaboujokh@gmail.com., Repetto A; Servicio de Medicina Nuclear del Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, Spain., Rodriguez Gasén A; Servicio Medicina Nuclear del Hospital Universitario de Bellvitge, Barcelona, Spain., Vercher Conejero JL; Servicio Medicina Nuclear del Hospital Universitario de Bellvitge, Barcelona, Spain., Bello Arques P; Hospital La Fe de Valencia, Valencia, Spain., Cambil Molina T; Servicio de Medicina Nuclear del Hospital Universitario Virgen Marcarena, Sevilla, Spain., Vallejo Casas JA; Hospital Universitario Reina Sofía. IMIBIC. Universidad de Córdoba, Córdoba, Spain.
Jazyk: angličtina
Zdroj: Revista espanola de medicina nuclear e imagen molecular [Rev Esp Med Nucl Imagen Mol (Engl Ed)] 2023 Sep-Oct; Vol. 42 (5), pp. 325-334. Date of Electronic Publication: 2023 Jul 11.
DOI: 10.1016/j.remnie.2023.07.003
Abstrakt: Radioiodine therapy represents a fundamental pillar in the routine adjuvant therapy of patients with high-risk differentiated thyroid carcinoma. However, a non-negligible percentage of these patients will develop iodine refractoriness, showing a worse prognosis, as well a lower survival, which demonstrates a clear need to explore different therapeutic approaches. Iodine refractory patient treatment continues to be a challenge, currently having different novel therapeutic options that should be known by the different specialties related to differentiated thyroid carcinoma (DTC). The aim of this work is to review iodine refractory thyroid carcinoma treatment, focusing especially on the definition of iodine refractoriness, highlighting its importance due to its high mortality, and introducing the different therapeutic options available for these patients.
(Copyright © 2023 Sociedad Española de Medicina Nuclear e Imagen Molecular. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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