Uncovering the link between air pollution and neurodevelopmental alterations during pregnancy and early life exposure: A systematic review.

Autor: Ruiz-Sobremazas D; Department of Psychology, Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain., Rodulfo-Cárdenas R; Universitat Rovira i Virgili, Research Group in Neurobehavior and Health (NEUROLAB), Tarragona, Spain; Universitat Rovira i Virgili, Department of Psychology and Research Center for Behavior Assessment (CRAMC), Tarragona, Spain; Universitat Rovira i Virgili, Laboratory of Toxicology and Environmental Health, School of Medicine, Reus, Spain., Ruiz-Coca M; Department of Psychology, Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain., Morales-Navas M; Department of Psychology, Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain., Teresa Colomina M; Universitat Rovira i Virgili, Research Group in Neurobehavior and Health (NEUROLAB), Tarragona, Spain; Universitat Rovira i Virgili, Department of Psychology and Research Center for Behavior Assessment (CRAMC), Tarragona, Spain; Universitat Rovira i Virgili, Laboratory of Toxicology and Environmental Health, School of Medicine, Reus, Spain., López-Granero C; Department of Psychology, University of Zaragoza, Zaragoza, Spain., Sánchez-Santed F; Department of Psychology, Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain., Perez-Fernandez C; Department of Psychology, Health Research Center (CEINSA), Almeria University, 04120 Almeria, Spain. Electronic address: cpf603@ual.es.
Jazyk: angličtina
Zdroj: Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2023 Sep; Vol. 152, pp. 105314. Date of Electronic Publication: 2023 Jul 12.
DOI: 10.1016/j.neubiorev.2023.105314
Abstrakt: Air pollution plays, nowadays, a huge role in human's health and in the personal economy. Moreover, there has been a rise in the prevalence of neurodevelopmental disorders like the Autism Spectrum Disorder (ASD) in recent years. Current scientific studies have established a link between prenatal or perinatal exposure to environmental pollutants and ASD. This systematic review summarizes the current literature available about the relationship between exposure to air pollutants (particulate matter [PM], Second Organic Aerosols [SOA], Diesel Exhaust [DE], and Traffic Related Air Pollution [TRAP]) and neurodevelopmental disorders in preclinical models using rats and mice. The articles were selected and filtered using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology, and bias-evaluated using the SYstematic Review Centre for Laboratory animal Experimentation (SYRCLE) tool. Overall, our findings suggest that air pollutants are associated with negative developmental outcomes characterized by ASD-like behaviors, abnormal biochemical patterns, and impaired achievement of developmental milestones in rodents. However, there is not sufficient information in certain domains to establish a clear relationship. Short phrases for indexing terms: Air pollution affects neurodevelopment; PM exposure modifies glutamate system; Prenatal exposure combined with postnatal affect more to behavioral / cognitive domain; Air pollution modifies social behavior in rodents; Cognitive deficits can be detected after gestational exposure to air pollution.
Competing Interests: Declaration of Competing Interest All authors have declared that no financial or personal relationships have influenced in writing this article. No author claimed conflict of interest to disclose. No further affiliations with any organization that may have a financial or political interest in the subject matter discussed in this work are present. The present research was conducted solely for academic purposes and have not received any further support from any external sources that may have influenced our findings or conclusions.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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