Sex- and timing-specific effects of fasting and caloric restriction.
| Autor: | Hofer SJ; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria; Field of Excellence BioHealth, University of Graz, Graz, Austria; BioTechMed Graz, Graz, Austria., Madeo F; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria; Field of Excellence BioHealth, University of Graz, Graz, Austria; BioTechMed Graz, Graz, Austria. Electronic address: frank.madeo@uni-graz.at. |
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| Jazyk: | angličtina |
| Zdroj: | Cell metabolism [Cell Metab] 2023 Jul 11; Vol. 35 (7), pp. 1091-1093. |
| DOI: | 10.1016/j.cmet.2023.06.001 |
| Abstrakt: | Optimizing food quantity and fasting time may improve health and lifespan. We summarize emerging knowledge on sex, age, and circadian timing as important determinants for the efficacy of dietary interventions and highlight results from Duregon et al. pointing to a favorable combination of caloric restriction (CR) and fasting in aged female mice. Competing Interests: Declaration of interests F.M. is a scientific cofounder of Samsara Therapeutics, a company that develops new pharmacological autophagy inducers. F.M. has equity interests in and is an advisor of The Longevity Labs (TLL). (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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