| Autor: |
Ponnimbaduge Perera P; Department of Biology, University of Nevada, Reno, Nevada, USA; email: mistyriddle@unr.edu., Perez Guerra D; Department of Biology, University of Nevada, Reno, Nevada, USA; email: mistyriddle@unr.edu., Riddle MR; Department of Biology, University of Nevada, Reno, Nevada, USA; email: mistyriddle@unr.edu. |
| Jazyk: |
angličtina |
| Zdroj: |
Annual review of cell and developmental biology [Annu Rev Cell Dev Biol] 2023 Oct 16; Vol. 39, pp. 23-44. Date of Electronic Publication: 2023 Jul 12. |
| DOI: |
10.1146/annurev-cellbio-012023-014003 |
| Abstrakt: |
Our understanding of cell and developmental biology has been greatly aided by a focus on a small number of model organisms. However, we are now in an era where techniques to investigate gene function can be applied across phyla, allowing scientists to explore the diversity and flexibility of developmental mechanisms and gain a deeper understanding of life. Researchers comparing the eyeless cave-adapted Mexican tetra, Astyanax mexicanus , with its river-dwelling counterpart are revealing how the development of the eyes, pigment, brain, cranium, blood, and digestive system evolves as animals adapt to new environments. Breakthroughs in our understanding of the genetic and developmental basis of regressive and constructive trait evolution have come from A. mexicanus research. They include understanding the types of mutations that alter traits, which cellular and developmental processes they affect, and how they lead to pleiotropy. We review recent progress in the field and highlight areas for future investigations that include evolution of sex differentiation, neural crest development, and metabolic regulation of embryogenesis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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