Calcineurin Inhibitor-Induced Type IV Renal Tubular Acidosis in Post-Bone Marrow Transplant: Review of Pathophysiology and Principles of Management.
| Autor: | Al-Omairi A; Child Health, Sultan Qaboos University Hospital, Muscat, OMN., Abdulnasser Obaid M; Child Health, Sultan Qaboos University Hospital, Muscat, OMN., Agrawal I; Child Health, Sultan Qaboos University Hospital, Muscat, OMN., Abdalla A; Child Health, Sultan Qaboos University Hospital, Muscat, OMN., Al Rawas AH; Child Health, Sultan Qaboos University Hospital, Muscat, OMN. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Jun 10; Vol. 15 (6), pp. e40215. Date of Electronic Publication: 2023 Jun 10 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.40215 |
| Abstrakt: | Calcineurin inhibitors (CNI) are the mainstay of immunosuppressant medications in both bone marrow transplants and solid organ transplants. Nephrotoxicity is a well-known adverse effect of this group. Type IV renal tubular acidosis is a potentially under-recognized complication. Here we report a case of Omenn syndrome in a patient who underwent a bone marrow transplant and developed type IV renal tubular acidosis while on treatment with cyclosporine. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, AL-Omairi et al.) |
| Databáze: | MEDLINE |
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