| Autor: |
Zhou J; Fachbereich Pharmazie, Institut für Pharmazeutische Biologie und Biotechnologie, Philipps-Universität Marburg, Robert-Koch Straße 4, Marburg, 35037 Hessen, Germany.; School of Life Sciences, Hainan University, Haikou 570228, P. R. China., Wei H; Fachbereich Pharmazie, Institut für Pharmazeutische Biologie und Biotechnologie, Philipps-Universität Marburg, Robert-Koch Straße 4, Marburg, 35037 Hessen, Germany., Li SM; Fachbereich Pharmazie, Institut für Pharmazeutische Biologie und Biotechnologie, Philipps-Universität Marburg, Robert-Koch Straße 4, Marburg, 35037 Hessen, Germany. |
| Abstrakt: |
Four undescribed plant growth inhibitory indole derivatives, colletotriauxins A-D ( 1-4 ), along with two known analogues indole-3-acetic acid (IAA) ( 5 ) and its amide indole-3-acetamide ( 6 ), were isolated from the phytopathogenic fungus Colletotrichum gloeosporioides NRRL 45420. Their structures were elucidated by NMR and MS analyses. 1 and 2 are rhamnosides of indole-3-ethanol (tryptophol) and its methylated derivative, respectively. In the structures of 3 and 4 , the two terminal hydroxyl groups of hexitol and pentane-1,2,3,4,5-pentol are connected with indole-3-(2-methyl)-acetyl and acetyl moieties. Compounds 1-6 inhibit Lepidium sativum seedling growth. The inhibition activities of colletotriauxins for stem growth were even stronger than IAA, with compounds 3 and 4 as the most active ones. These results suggested that colletotriauxins could serve as potential candidates as herbicides. |
